Testing a new drug alone or with another drug for advanced cancer
Treatments studied
Part of Cancer clinical trials.
This study tests a new investigational drug called BI 3968621, given either by itself or with another drug called ezabenlimab, for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to find safe and effective doses and see if the combination helps shrink tumors or slow their growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have advanced cancer (solid tumor) that has spread or cannot be removed by surgery, and standard treatments have stopped working or are not available.
- You must have at least one tumor that can be measured by scans (outside the brain).
- You must be able to perform daily activities with minimal help (ECOG score 0 or 1).
- You must live at least 3 months from the start of treatment, in the doctor's opinion.
- If you have brain metastases, you may still be eligible if certain conditions are met.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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