Clin2
NCT07863765Possibly a fitNot yet recruiting

Study of enfortumab vedotin for advanced thyroid cancers and NUT carcinoma

Metastatic Differentiated Thyroid Gland CarcinomaMetastatic NUT CarcinomaMetastatic Thyroid Gland Anaplastic CarcinomaMetastatic Thyroid Gland Medullary CarcinomaRefractory Differentiated Thyroid Gland CarcinomaStage III Differentiated Thyroid Gland Carcinoma AJCC v8Stage III Thyroid Gland Medullary Carcinoma AJCC v8Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8

Treatments studied

Part of Cancer clinical trials.

This trial tests a drug called enfortumab vedotin for people with certain advanced thyroid cancers or NUT carcinoma that have not responded to other treatments. The drug is given by IV and aims to shrink or slow the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
56 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have one of these thyroid cancers that has spread or cannot be removed: differentiated thyroid cancer that no longer responds to radioactive iodine, anaplastic thyroid cancer, medullary thyroid cancer, or NUT carcinoma.
  • You have tried at least one previous treatment (like surgery, radiation, chemotherapy, or targeted therapy), but it is no longer working.
  • You have not previously taken enfortumab vedotin or a similar drug.
  • You are 18 years or older.
  • You are generally well enough to carry out daily activities (ECOG score 0 or 1).
  • Your blood counts, liver, and kidney function are within acceptable limits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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