Clinical trials
Deprescribing clinical trials
Below are recruiting deprescribing clinical trials, each written for real people, not researchers. We’re tracking 18 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05765656Recruiting
Doctors and pharmacists helping older adults reduce sleeping pills
This study will see if working closely with your doctor and pharmacist can help older adults safely reduce or stop taking medications for anxiety or sleep, like benzodiazepines.
NantesAges 65 years+ - NCT06129474Recruiting
Reducing unnecessary high-dose heartburn medication in adults
This study tests whether it is safe and helpful to reduce or stop daily high-dose heartburn medications (called PPIs) in patients who might not need them anymore. It is for adults who take a strong PPI every day and can communicate in German.
BernAges 18 years+ - NCT06193083Recruiting
Deprescribing views of patients with advanced cancer
This study asks patients with advanced cancer about their thoughts on stopping medications that may no longer be needed or could be harmful. It aims to understand patient perspectives to improve care.
La Roche-sur-YonAges 18 years+ - NCT06324045Recruiting
Deprescribing medicines for kidney disease patients
This study looks at whether carefully reducing or stopping some medicines (deprescribing) can help people with advanced kidney disease. The goal is to improve quality of life and avoid side effects from unnecessary medications.
DohaAges 18 years+ - NCT06629272Recruiting
Reducing Unnecessary Thyroid Hormone in Older Adults
This study is testing whether it’s safe to slowly reduce or stop thyroid hormone medication in older adults who may not need it. The goal is to improve health and avoid unnecessary treatment.
San Francisco, CaliforniaAges 65 years+ - NCT07114094Recruiting
Developing a tool to safely reduce medications in older adults
This study aims to create and test a tool that helps doctors decide which medications might be safely stopped or reduced for patients aged 60 and older. If you're an older adult visiting a general medicine or family medicine clinic, you may be able to help shape this tool.
Bangalore, KarnatakaAges 60 years+ - NCT07298993Enrolling by invitationPhase 4
Can older adults with heart failure safely stop beta-blockers?
This trial tests whether it is safe to gradually stop beta-blocker medication in older adults with heart failure with preserved ejection fraction (a type of heart failure where the heart pumps normally but is stiff). It aims to improve quality of life by reducing unnecessary medications.
Pleasanton, CaliforniaAges 60 years+ - NCT05842928Recruiting
Deprescribing risky medicines in older adults with many medications
This study tests a patient-centered plan to safely reduce certain medicines that may cause side effects in older people who take many drugs. It aims to improve safety and comfort by lowering unnecessary use while keeping you well.
BielefeldAges 65 years+ - NCT06467019Recruiting
Reducing benzodiazepine use with educational information
This trial tests if showing educational information to people about reducing or stopping benzodiazepines (a type of sleep or anxiety medication) helps them safely use less. You may be able to join if you're an adult patient at this specific clinic and not already in a similar study.
Vilanova i la Geltrú, BarcelonaAges 18–99 - NCT06771999Recruiting
Deprescribing medications in cancer patients: a pharmacist's help
This trial tests whether a clinical pharmacist's educational session can help you and your doctor safely reduce or stop unneeded medications. It's for people receiving palliative care for cancer.
Baia Mare, MaramureşAges 18 years+ - NCT06858384Recruiting
Optimizing PPI use through education and intervention
This trial tests whether educating doctors can reduce unnecessary prescriptions of proton pump inhibitors (PPIs, a type of acid-reducing medicine). If you are an adult patient who has been prescribed a PPI that might not be needed, your doctor may join this study to improve your care.
Ras al-KhaimahAges 18 years+ - NCT07022990Recruiting
Better medication management for WTC responders
This study helps WTC responders aged 50+ who take certain common medications learn how to manage them better and stay healthy as they age. You must already be enrolled in Mount Sinai's aging study.
New York, New YorkAges 50 years+ - NCT07278609Recruiting
Safer medication use for older adults with rheumatic conditions
This study tests a program to help doctors choose safer medications for people aged 60 and older who have arthritis or other rheumatic conditions. It aims to reduce the use of potentially harmful drugs and improve overall medication safety.
Montreal, QuebecAges 60 years+ - NCT07343193Recruiting
Reducing antipsychotic medication: a case study
This study looks at safely reducing or stopping antipsychotic medication in adults with psychotic disorders who are stable and interested in trying. It aims to understand how to best support patients during this process.
StrasbourgAges 18 years+ - NCT07454824Recruiting
Aligning medications with what matters most: patient portal trial
This study tests whether a patient portal tool can help older adults with memory problems and their care partners adjust medications to better match their personal goals and values. It is for people who are 65 or older, have mild cognitive impairment or dementia, are taking a medication that may not be ideal for their age, and use the patient portal.
Baltimore, MarylandAges 65 years+ - NCT07543432Recruiting
Should Advanced Cancer Patients Stop Taking Cholesterol Medication?
This study explores whether patients with advanced cancer who are receiving end-of-life care can safely stop taking statin medications (cholesterol drugs). Researchers want to understand if continuing these drugs at this stage of illness is still beneficial or if stopping them might improve quality of life.
StockholmAges 18 years+ - NCT07281131Enrolling by invitation
Medication check before your doctor visit
This study tests if a pre-visit questionnaire helps older adults and their doctors talk about certain medications. You may be asked about taking a statin for heart health or stopping a high-risk medication.
Boston, MassachusettsAges 65 years+ - NCT06304428Enrolling by invitation
Preventing falls and fractures by optimizing medications in nursing homes
This study tests whether carefully reviewing and adjusting medications in a skilled nursing facility can help prevent future fractures and injuries in older adults who were recently hospitalized for a broken bone.
Boston, MassachusettsAges 65 years+
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Common questions
- Are there clinical trials for deprescribing?
- Yes. Clin2 currently lists 18 recruiting deprescribing studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deprescribing trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deprescribing trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.