Clinical trials · California
Glaucoma, Open-Angle clinical trials in California
We’re tracking 11 recruiting glaucoma, open-angle studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06822738RecruitingPhase 3
Study of XEN63 gel stent for glaucoma patients
This trial tests a new gel stent (XEN63) to lower eye pressure in adults with glaucoma. It compares two ways of putting the stent in the eye, and may help people who have not had success with other treatments.
Culver City, CaliforniaAges 45 years+ - NCT07520175Enrolling by invitation
Bio-Reinforced Canaloplasty for Open-Angle Glaucoma
This study tests a newer surgical procedure called bio-reinforced canaloplasty, which helps fluid drain better from the eye to lower eye pressure in people with open-angle glaucoma. Researchers will follow patients to see how well this procedure works and how safe it is.
Chico, CaliforniaAges Any age - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Petaluma, CaliforniaAges 18 years+ - NCT05626426Recruiting
Electrical stimulation for optic nerve damage from glaucoma
This trial studies whether electrical stimulation can help improve vision in people with glaucoma-related optic nerve damage. You may qualify if your visual field test shows moderate to severe loss and your eye pressure is stable.
Palo Alto, CaliforniaAges 18 years+ - NCT06267274RecruitingPhase 1
Comparing two forms of bimatoprost for glaucoma or high eye pressure
This trial tests whether a new formulation of bimatoprost works as well as an existing one to lower eye pressure in people with chronic open-angle glaucoma or ocular hypertension. It involves multiple eye drop doses and checks for safety and effectiveness.
Bakersfield, CaliforniaAges 18 years+ - NCT06685211Recruiting
Electrical stimulation for vision in glaucoma
This trial tests whether gentle electrical stimulation can help improve vision in people with moderate vision loss from glaucoma. It might offer a new way to strengthen remaining vision.
Palo Alto, CaliforniaAges 18 years+ - NCT07354477RecruitingPhase 2
New eye drop for glaucoma and diabetic retinopathy
This trial tests a new eye drop (QLS-111) to see if it improves blood flow in the back of the eye. It may help people with mild to moderate glaucoma or stable diabetic retinopathy by reducing pressure inside the eye and nourishing the optic nerve.
Palo Alto, CaliforniaAges 18 years+ - NCT07220876Recruiting
VisiPlate implant for hard-to-control open-angle glaucoma
This trial tests a new device called VisiPlate that is placed in the eye to help lower pressure for people with hard-to-control open-angle glaucoma. It may be an option if standard treatments haven't worked well enough.
Sacramento, CaliforniaAges 45 years+ - NCT07480343Enrolling by invitation
Five-year follow-up after CREST glaucoma study
This study follows up with people who finished the CREST study to check how their eyes are doing 5 years later. It looks at the long-term results of a prior glaucoma treatment.
Newport Beach, CaliforniaAges Any age - NCT07290244RecruitingPhase 1
Testing ER-100 safety for glaucoma or NAION patients
This trial tests whether a new drug, ER-100, is safe for people with glaucoma or a sudden optic nerve injury called NAION. It aims to see if the drug can be given without serious side effects.
Glendale, CaliforniaAges 40–85 - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Petaluma, CaliforniaAges 18 years+
Glaucoma, Open-Angle trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting glaucoma, open-angle studies listed above.
- North Bay Eye Associates · 4 studies
- Eye Research Foundation · 3 studies
- Byers Eye Institute at Stanford University · 2 studies
- CREST Site 05
- Global Research Management, Inc.
- LA Glaucoma Group
- National Clinical Trials
- Ridge Eye Care, Inc.
What taking part in a glaucoma, open-angle study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Glaucoma, Open-Angle trials in other states
Common questions
- Are there glaucoma, open-angle clinical trials in California?
- Yes. We're currently tracking 11 recruiting glaucoma, open-angle studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a glaucoma, open-angle study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a glaucoma, open-angle trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New glaucoma, open-angle studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.