Clinical trials
Glaucoma, Open-Angle clinical trials
Below are recruiting glaucoma, open-angle clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+ - NCT06057051Recruiting
Stent implant for mild to moderate open-angle glaucoma
This trial studies a tiny implant called iStent Infinite that helps drain fluid from the eye to lower pressure in people with mild to moderate open-angle glaucoma. It may offer a new way to manage the condition.
Cincinnati, OhioAges 35 years+ - NCT05710198RecruitingPhase 3
Citicoline eye drops to slow vision field loss in glaucoma
This Phase 3 trial tests whether citicoline 2% eye drops can help slow worsening of the visual field in adults with open-angle glaucoma. If you qualify, you would be monitored with repeated eye tests to see if your vision field stays more stable over time.
Milan, MIAges 18 years+ - NCT05405868RecruitingPhase 3
Nicotinamide for early to moderate open-angle glaucoma
This trial tests whether nicotinamide (a form of vitamin B3) can slow vision changes from open-angle glaucoma. It compares nicotinamide versus a placebo (inactive pill) in adults with early to moderate disease.
Belfast, Northern IrelandAges 18 years+ - NCT07847073RecruitingPhase 4
Comparing eye drops for glaucoma and their effect on the optic nerve
This trial tests two eye drops—Rhopressa (netarsudil) and timolol—at lowering eye pressure in people with open-angle glaucoma. The study uses a special camera to see if treatment helps protect the nerve cells in the back of the eye.
Bloomington, IndianaAges 18 years+ - NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT07700498Recruiting
Combined cataract and glaucoma surgery for new patients
This trial tests a single surgery to treat both glaucoma and cataracts at the same time. It is for people who have not had any prior glaucoma treatment and need cataract surgery.
Ningxia, NingxiaAges 40–85 - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT06201455Recruiting
Glaucoma surgery study for people with controlled eye pressure and cataracts
This study tests a new surgery that combines cataract removal with a glaucoma procedure to lower eye pressure in people with primary open-angle glaucoma. It's for people whose eye pressure is controlled with 1 to 4 medications but who also have significant cataracts.
Guangzhou, GuangdongAges 40–85 - NCT07520175Enrolling by invitation
Bio-Reinforced Canaloplasty for Open-Angle Glaucoma
This study tests a newer surgical procedure called bio-reinforced canaloplasty, which helps fluid drain better from the eye to lower eye pressure in people with open-angle glaucoma. Researchers will follow patients to see how well this procedure works and how safe it is.
Chico, CaliforniaAges Any age - NCT07480343Enrolling by invitation
Five-year follow-up after CREST glaucoma study
This study follows up with people who finished the CREST study to check how their eyes are doing 5 years later. It looks at the long-term results of a prior glaucoma treatment.
Newport Beach, CaliforniaAges Any age - NCT06792422RecruitingPhase 4
Oral semaglutide for open-angle glaucoma
This trial tests if an oral medication called semaglutide can help people with open-angle glaucoma. It aims to see if it can protect the optic nerve and manage eye pressure.
Glostrup MunicipalityAges 45 years+ - NCT07454447Recruiting
Eye exam after new glaucoma surgery
This trial uses a special ultrasound to look at the eye after a certain type of glaucoma surgery. It helps doctors see how well the surgery is working for people with open-angle glaucoma.
Minya, Minya GovernorateAges Any age - NCT07462000Recruiting
Eye fluid and tissue analysis in glaucoma and cataract
This study collects eye fluid and tissue samples during planned cataract or combined cataract-glaucoma surgery to analyze differences between people with and without glaucoma. It may help researchers understand eye disease better.
WarsawAges 18 years+ - NCT07408154Recruiting
Direct vs standard laser for glaucoma: which works better?
This study compares a direct laser treatment to the standard laser for glaucoma or high eye pressure. It aims to see if the direct method is just as effective and possibly safer.
Charleston, South CarolinaAges 18 years+ - NCT07396441RecruitingPhase 4
Kelulut honey therapy for juvenile glaucoma
This trial tests if adding Kelulut honey to standard treatment can help protect the optic nerve in young people with juvenile open-angle glaucoma. It looks at eye pressure, nerve thickness, and dry eye symptoms.
Kota Bharu, KelantanAges 15–40 - NCT07358650Recruiting
MIST device for lowering eye pressure in glaucoma
This study tests a new device called MIST that is placed inside the eye to help lower eye pressure in people with primary open-angle glaucoma. It may be an option for those whose pressure is still too high despite using eye drops.
Dieppe, New BrunswickAges 40 years+ - NCT07354009Recruiting
Stent implant for lowering eye pressure in open-angle glaucoma
This trial tests a small stent to help drain fluid from the eye and lower pressure in people who have both open-angle glaucoma and cataracts. The stent is placed during routine cataract surgery.
HangzhouAges 18–90 - NCT07335211RecruitingPhase 3
Testing a new eye drop for glaucoma or high eye pressure
This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.
SeoulAges 19 years+ - NCT06865235Recruiting
Glaucoma and cataract surgery with a new device
This trial tests a surgery that combines cataract removal with a new technique to lower eye pressure in people who have both primary open-angle glaucoma and cataracts. It aims to see if this combined surgery is safe and effective.
Belo Horizonte, Minas GeraisAges 40 years+ - NCT07322965Recruiting
Citicoline and DHA supplement for glaucoma patients
This trial tests whether a dietary supplement (DHA + citicoline) can help protect vision in people with glaucoma. You may qualify if you have confirmed glaucoma in at least one eye and are between 50 and 75 years old.
Barcelona, BarcelonaAges 50–75
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Glaucoma, Open-Angle trials by city
Studies with a site in or near these metro areas.
Glaucoma, Open-Angle trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for glaucoma, open-angle?
- Yes. Clin2 currently lists 59 recruiting glaucoma, open-angle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glaucoma, open-angle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glaucoma, open-angle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.