Clinical trials
Glaucoma, Open-Angle clinical trials
Below are recruiting glaucoma, open-angle clinical trials, each written for real people, not researchers. We’re tracking 63 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT06822738RecruitingPhase 3
Study of XEN63 gel stent for glaucoma patients
This trial tests a new gel stent (XEN63) to lower eye pressure in adults with glaucoma. It compares two ways of putting the stent in the eye, and may help people who have not had success with other treatments.
Glendale, ArizonaAges 45 years+ - NCT07520175Enrolling by invitation
Bio-Reinforced Canaloplasty for Open-Angle Glaucoma
This study tests a newer surgical procedure called bio-reinforced canaloplasty, which helps fluid drain better from the eye to lower eye pressure in people with open-angle glaucoma. Researchers will follow patients to see how well this procedure works and how safe it is.
Chico, CaliforniaAges Any age - NCT03423758Recruiting
Genetic study of eye diseases: PXF, angle-closure and open glaucoma
This study looks at blood or DNA-related factors that may explain why certain glaucoma and related eye conditions happen. It may help researchers understand risk and causes across different glaucoma types.
ViennaAges 21–105 - NCT03870230Recruiting
Study of eye blood-flow signals in glaucoma and healthy eyes
This study compares eye blood-flow/brain-eye communication signals in people with glaucoma (or high eye pressure) versus people with normal eye tests. It may help researchers understand how glaucoma develops and progresses.
ViennaAges 18 years+ - NCT03921931Recruiting
Test retinal responses to light in healthy eyes or eye disease
This is a small pilot study that measures how parts of the retina change before and after light stimulation. It may help researchers understand eye function in people with normal vision or specific eye conditions like glaucoma or dry age-related macular degeneration (AMD).
Vienna, State of ViennaAges 18 years+ - NCT07700498Recruiting
Combined cataract and glaucoma surgery for new patients
This trial tests a single surgery to treat both glaucoma and cataracts at the same time. It is for people who have not had any prior glaucoma treatment and need cataract surgery.
Ningxia, NingxiaAges 40–85 - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT05264818Recruiting
Study measures eye surface sugar layer in glaucoma
This study looks at a thin “sugar coating” on the inside surface of the eye (the endothelial glycocalyx) in people with primary open-angle glaucoma and compares it with people without optic nerve disease. The results may help researchers better understand how glaucoma affects the eye.
ParisAges 18 years+ - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05405868RecruitingPhase 3
Nicotinamide for early to moderate open-angle glaucoma
This trial tests whether nicotinamide (a form of vitamin B3) can slow vision changes from open-angle glaucoma. It compares nicotinamide versus a placebo (inactive pill) in adults with early to moderate disease.
Belfast, Northern IrelandAges 18 years+ - NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+ - NCT05624398Recruiting
Hydrus stent plus cataract surgery for mild glaucoma
This study looks at outcomes for people with mild glaucoma who need cataract surgery, comparing how well the Hydrus stent works when placed during cataract surgery. The goal is to see whether this combined approach keeps eye pressure and vision stable with fewer issues.
Fayetteville, ArkansasAges 45 years+ - NCT05626426Recruiting
Electrical stimulation for optic nerve damage from glaucoma
This trial studies whether electrical stimulation can help improve vision in people with glaucoma-related optic nerve damage. You may qualify if your visual field test shows moderate to severe loss and your eye pressure is stable.
Palo Alto, CaliforniaAges 18 years+ - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05710198RecruitingPhase 3
Citicoline eye drops to slow vision field loss in glaucoma
This Phase 3 trial tests whether citicoline 2% eye drops can help slow worsening of the visual field in adults with open-angle glaucoma. If you qualify, you would be monitored with repeated eye tests to see if your vision field stays more stable over time.
Milan, MIAges 18 years+ - NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+ - NCT05885022Recruiting
Testing a glaucoma device during eye surgery planning
This study checks whether the Calibreye System can be used safely and effectively for people with certain types of glaucoma. It may help doctors better assess the eye before treatment, especially for selecting the right surgical approach.
ChennaiAges 18 years+ - NCT06057051Recruiting
Stent implant for mild to moderate open-angle glaucoma
This trial studies a tiny implant called iStent Infinite that helps drain fluid from the eye to lower pressure in people with mild to moderate open-angle glaucoma. It may offer a new way to manage the condition.
Cincinnati, OhioAges 35 years+ - NCT06066645RecruitingPhase 4
Travoprost implant plus iStent for glaucoma
This trial tests a tiny implant that slowly releases travoprost (a pressure-lowering medicine) inside the eye, combined with a small stent (iStent) to help drain fluid. It's for people with open-angle glaucoma or high eye pressure who need to lower their eye pressure.
Oklahoma City, OklahomaAges 18 years+ - NCT06201455Recruiting
Glaucoma surgery study for people with controlled eye pressure and cataracts
This study tests a new surgery that combines cataract removal with a glaucoma procedure to lower eye pressure in people with primary open-angle glaucoma. It's for people whose eye pressure is controlled with 1 to 4 medications but who also have significant cataracts.
Guangzhou, GuangdongAges 40–85 - NCT06246136Recruiting
Laser treatment for glaucoma during cataract surgery
This study tests a new laser treatment (ELIOS) for people with open-angle glaucoma who also need cataract surgery. It aims to see if the laser is safe and effective at lowering eye pressure while removing the cataract.
LeuvenAges 40 years+ - NCT06267274RecruitingPhase 1
Comparing two forms of bimatoprost for glaucoma or high eye pressure
This trial tests whether a new formulation of bimatoprost works as well as an existing one to lower eye pressure in people with chronic open-angle glaucoma or ocular hypertension. It involves multiple eye drop doses and checks for safety and effectiveness.
Bakersfield, CaliforniaAges 18 years+ - NCT06289491Recruiting
Hydrus Microstent vs Goniotomy during cataract surgery
This study compares two procedures done during cataract surgery: placing a tiny stent (Hydrus Microstent) or performing a goniotomy (a small cut in the eye's drainage tissue). Both aim to lower eye pressure in people with mild to moderate open-angle glaucoma.
Boston, MassachusettsAges 40–85
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Glaucoma, Open-Angle trials by city
Studies with a site in or near these metro areas.
Glaucoma, Open-Angle trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for glaucoma, open-angle?
- Yes. Clin2 currently lists 63 recruiting glaucoma, open-angle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glaucoma, open-angle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glaucoma, open-angle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.