Clinical trials · California
HIV Prevention clinical trials in California
We’re tracking 9 recruiting hiv prevention studies with a site in California — including Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06586151Recruiting
HIV prevention program for gender-diverse teens
This study tests a text-message program to help prevent HIV in teens who are transgender, non-binary, or gender-diverse. It aims to see if the program can support healthy choices and reduce risk.
San Clemente, CaliforniaAges 14–18 - NCT07473778Recruiting
Study of Lenacapavir for HIV Prevention
This trial tests a new medication, lenacapavir, to see how well it works for preventing HIV. It is for people who want or need PrEP (a medicine to prevent HIV) and are interested in learning about different options.
Beverly Hills, CaliforniaAges 18 years+ - NCT07683117Recruiting
PEP/PrEP through pharmacist prescribing (PEPPI)
This study looks at how well pharmacists can provide PEP and PrEP (HIV prevention pills) using a special software called PEPPI. It aims to make it easier and faster for people to get these medicines.
Del Mar, CaliforniaAges 18 years+ - NCT04855773Recruiting
Mobile text-message support to help people stay on PrEP
This trial tests whether phone-based (iPhone/Android) text-message support can improve how consistently people use PrEP, an HIV prevention medicine. It may help you stay on track with refills and clinic visits, especially if you’re at higher risk of stopping PrEP.
San Francisco, CaliforniaAges 15 years+ - NCT06848686Recruiting
HIV service ambassador program for people who use drugs
This trial trains people who use drugs to talk with friends in their social network about HIV testing and services. It aims to encourage more people to get tested and linked to care.
San Diego, CaliforniaAges 18 years+ - NCT06230367Recruiting
Text program for HIV prevention for young guys who like guys
This trial tests a text-messaging program to help young guys who have sex with guys stay HIV-negative. It's designed for teens and young adults who own a cell phone and can take a quick HIV test at home.
San Clemente, CaliforniaAges 13–22 - NCT07433985Recruiting
California mobile app study for men after jail release
This study tests a mobile app to help men recently released from jail or prison who use drugs or have sex with men stay healthy and avoid HIV. It's for people who don't have HIV and live in certain California counties.
Oakland, CaliforniaAges 18–59 - NCT07467018Recruiting
Mobile van study of a long-acting HIV prevention shot
This study tests if giving a long-acting HIV prevention shot (lenacapavir) from a mobile medical van can reach people at risk for HIV in Los Angeles County. You may be able to join if you are HIV negative, at risk for HIV, and are willing to try a shot instead of a daily pill.
Santa Monica, CaliforniaAges 18 years+ - NCT07044297RecruitingPhase 3
A study of a new long-acting shot to prevent HIV
This study tests an investigational long-acting shot (MK-8527) to prevent HIV. It is for HIV-negative people who are at higher risk through anal sex without condoms, and who have not used other long-acting HIV prevention before.
Los Angeles, CaliforniaAges 16 years+
HIV Prevention trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting hiv prevention studies listed above.
- Center for Innovative Public Health Research · 2 studies
- Bridge HIV CRS
- CAL-PEP
- EmpoweRx, Inc
- Family Health Centers of San Diego
- Kindful Restoration
- Mills Clinical Research
- Pacific Oaks Medical Group
What taking part in a hiv prevention study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
HIV Prevention trials in other states
Common questions
- Are there hiv prevention clinical trials in California?
- Yes. We're currently tracking 9 recruiting hiv prevention studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a hiv prevention study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a hiv prevention trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New hiv prevention studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.