Clinical trials
HIV Prevention clinical trials
Below are recruiting hiv prevention clinical trials, each written for real people, not researchers. We’re tracking 101 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07218211RecruitingPhase 4
Injectable PrEP study for Latine transgender women and gay men
This study offers a long-acting injectable form of PrEP (lenacapavir) to prevent HIV in Latine transgender women and gay men in the South. It aims to make HIV prevention easier by providing a shot instead of a daily pill.
Durham, North CarolinaAges 18 years+ - NCT06586151Recruiting
HIV prevention program for gender-diverse teens
This study tests a text-message program to help prevent HIV in teens who are transgender, non-binary, or gender-diverse. It aims to see if the program can support healthy choices and reduce risk.
San Clemente, CaliforniaAges 14–18 - NCT07625917Recruiting
Testing an online HIV prevention program for people who inject drugs
This study tests whether an internet-based HIV prevention program works for people who use injection drugs. Researchers want to see if online tools can help reduce HIV risk and improve health outcomes.
The Bronx, New YorkAges 18 years+ - NCT07509827Recruiting
App-based program to help prevent HIV and reduce stigma
This study tests a mobile health program to help young transgender women prevent HIV and cope with stigma. Participants use an app and are not yet taking PrEP daily or have trouble sticking with it.
Bangkok, BangkapiAges 18–29 - NCT06506188Recruiting
Improving HIV prevention for breastfeeding women in Malawi
This study looks at how to make it easier for women in Malawi to stay on PrEP after giving birth while breastfeeding. Researchers will check medical records and ask some women to do a short survey and a finger stick blood test.
LilongweAges 15–99 - NCT05163301Recruiting
Alcohol relapse prevention for adults living with HIV
This study looks at ways to help people with HIV reduce the chance of heavy drinking coming back after a period of lower-risk drinking. It will use regular patient-reported check-ins about alcohol use to understand relapse patterns and test the approach’s impact.
Baltimore, MarylandAges 18 years+ - NCT05897099Recruiting
Telehealth harm-reduction for people at HIV risk
This study tests whether a telehealth program can reduce harm and lower HIV risk by helping with safer syringe use. It may help if you have recent syringe exchange use and are not currently on HIV prevention pills.
Miami, FloridaAges 18 years+ - NCT06900829Recruiting
HIV testing program for European hospitals
This trial helps hospitals find undiagnosed HIV by improving testing and care. It supports healthcare teams to identify HIV in people with certain conditions and ensures those diagnosed get connected to treatment.
GhentAges 18 years+ - NCT06003192Recruiting
Screen Smart: Boosting HIV testing in teens
This trial tests a digital health tool to help increase HIV screening and prevention among teenagers visiting the emergency department. If you are 15 to 21 years old, you may be able to join and help improve how we offer these services.
Columbus, OhioAges 15–21 - NCT06096324Recruiting
Education and job support for HIV prevention in young adults
This study is testing a program that combines education and job support to help young adults in Baltimore stay healthy and prevent HIV. It aims to see if this combined approach works better than education alone.
Baltimore, MarylandAges 18–24 - NCT07298785Recruiting
HIV prevention study led by peers for women
This study tests a peer-led approach to HIV prevention for women. It looks at whether having a peer (someone like you) help choose and use prevention tools can work better than standard care.
KampalaAges 15 years+ - NCT07473778Recruiting
Study of Lenacapavir for HIV Prevention
This trial tests a new medication, lenacapavir, to see how well it works for preventing HIV. It is for people who want or need PrEP (a medicine to prevent HIV) and are interested in learning about different options.
Birmingham, AlabamaAges 18 years+ - NCT03795376Recruiting
Dat'Aids prevention study for HIV, hepatitis, and STI screening
This study offers prevention-focused care and testing for people who may have been exposed to HIV, hepatitis, or other STIs. It tests ways to support safer health decisions and timely treatment when needed.
BelfortAges 18 years+ - NCT06056544Enrolling by invitation
HIV prevention support for Black men who have sex with men
This study tests a personalized care coordination program to help Black men who have sex with men stay on HIV prevention. It focuses on men who are new to or have stopped PrEP and want to reduce their HIV risk.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07292584Recruiting
Digital toolkit to help women start PrEP
This trial tests a digital toolkit to help women start taking PrEP, a medication that prevents HIV. It looks at whether the toolkit makes it easier for women to take PrEP consistently.
Birmingham, AlabamaAges 18 years+ - NCT07002866Recruiting
PrEP access and adherence study for young women in Uganda
This study tests a program to help adolescent girls and young women at high risk of HIV take PrEP consistently. It aims to improve access and adherence to PrEP, a daily pill that prevents HIV.
St Louis, MissouriAges 15–24 - NCT06872307Recruiting
Helping Black men stay on PrEP
This study tests a new way to help Black men who have sex with men stay on PrEP (HIV prevention pills) over time. If you are at risk for HIV and have stopped taking PrEP for at least a month, you may be able to join and get support to keep taking it.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07672717RecruitingPhase 1
Cabotegravir and hormone interaction study for HIV prevention
This study tests how a long-acting injectable HIV prevention drug (cabotegravir) works in people who also use hormone therapy (like birth control or gender-affirming hormones). The goal is to see if the hormones affect how well the drug prevents HIV. If you are HIV-negative, use hormones, and meet other health criteria, you may be able to join.
Baltimore, MarylandAges 19 years+ - NCT07683117Recruiting
PEP/PrEP through pharmacist prescribing (PEPPI)
This study looks at how well pharmacists can provide PEP and PrEP (HIV prevention pills) using a special software called PEPPI. It aims to make it easier and faster for people to get these medicines.
Del Mar, CaliforniaAges 18 years+ - NCT07076043RecruitingPhase 4
HIV prevention for young women getting reproductive health care
This study offers different forms of HIV prevention medicine (PrEP) to young women ages 18–30 who are visiting clinics for reproductive health services like family planning or postnatal care. It aims to see which delivery method works best for you.
Thika, Kiambu CountyAges 18–30 - NCT04855773Recruiting
Mobile text-message support to help people stay on PrEP
This trial tests whether phone-based (iPhone/Android) text-message support can improve how consistently people use PrEP, an HIV prevention medicine. It may help you stay on track with refills and clinic visits, especially if you’re at higher risk of stopping PrEP.
San Francisco, CaliforniaAges 15 years+ - NCT06370923Recruiting
Using male peer networks for HIV prevention
This study tests if working with groups of male friends can help men better engage with HIV prevention services. It aims to find new ways to reach men who may not otherwise seek prevention tools.
Mutare, Manicaland ProvinceAges 18 years+ - NCT05320835Recruiting
Talk-based overdose prevention for people using opioids
This trial tests an overdose prevention approach for people who have used opioids recently. It aims to help reduce the risk of overdose by offering a structured prevention intervention.
Baltimore, MarylandAges 18 years+ - NCT06962033Recruiting
Pride III: Prison and HIV prevention study
This study looks at ways to improve HIV prevention and treatment for people on probation who have injected opioids. Researchers want to learn from your experiences to help create better services.
New Haven, ConnecticutAges 18 years+
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HIV Prevention trials by city
Studies with a site in or near these metro areas.
HIV Prevention trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for hiv prevention?
- Yes. Clin2 currently lists 101 recruiting hiv prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.