Clinical trials · Chicago, IL
HIV clinical trials in Chicago
We’re tracking 27 recruiting hiv studies with a site in or near Chicago — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT05719441RecruitingPhase 2
Testing HIV antibodies plus early HIV treatment for possible remission
This trial tests whether giving two powerful HIV-fighting antibodies (called broadly neutralizing monoclonal antibodies) along with starting standard HIV medications soon after infection can help control the virus without needing daily pills. If successful, it might allow people to take a 'treatment pause' while keeping their immune system healthy.
Chicago, IllinoisAges 18–70 - NCT07510048Recruiting
PrEP choice study for young men at higher risk for HIV
This study compares different ways to help young men learn about and choose PrEP, a medicine that prevents HIV. It aims to see which approach works best for starting and staying on PrEP.
Chicago, IllinoisAges 13–24 - NCT05848570Recruiting
Digital program for reducing HIV risk in SGM youth
This trial tests a digital health program (available with limited in-person contact) to help SGM young people reduce their risk of HIV. You may be a good fit if you’re in the right age range and have had certain types of sex in the last 6 months.
Chicago, IllinoisAges 13–34 - NCT05723653Recruiting
Cell phone social support for people not in HIV care
This study tests a social support intervention delivered through a “support person” (a confidant) to help people stay engaged in HIV care and improve viral suppression. It may help by strengthening support outside of clinic visits and making care easier to follow.
Chicago, IllinoisAges 18–49 - NCT07665372Recruiting
Liver transplant from donors with HIV for people with HIV
This study tests whether giving people with HIV a liver from an HIV-positive donor is safe and works well. It looks at infections, cancer risks, and long-term health after transplant.
Chicago, IllinoisAges 18 years+ - NCT07266831RecruitingPhase 2/Phase 3
New HIV treatment for people not yet on medication
This study tests a new combination medicine for people with HIV who have never taken treatment. It aims to see if it is safe and helps reduce the amount of virus in the blood.
Chicago, IllinoisAges 18 years+ - NCT06517693RecruitingPhase 1
HIV antibody safety study for newborns at risk
This study tests whether giving a combination of two lab-made antibodies (PGT121.414.LS and VRC07-523LS) to newborns exposed to HIV during pregnancy is safe and how the body processes them. It may help protect infants from getting HIV after birth.
Chicago, IllinoisAges Up to 3 days - NCT07473778Recruiting
Study of Lenacapavir for HIV Prevention
This trial tests a new medication, lenacapavir, to see how well it works for preventing HIV. It is for people who want or need PrEP (a medicine to prevent HIV) and are interested in learning about different options.
Chicago, IllinoisAges 18 years+ - NCT07040319RecruitingPhase 1/Phase 2
Hepatitis C treatment study for pregnant women
This study tests a medicine called glecaprevir/pibrentasvir for pregnant women with hepatitis C, with or without HIV. It aims to see how the medicine works in the body and if it is safe during pregnancy.
Chicago, IllinoisAges 16–45 - NCT06162897Recruiting
Case management for HIV or PrEP care support
This study tests whether pairing a case manager with people living with HIV or taking PrEP can help them stay in care and address financial or food problems.
Chicago, IllinoisAges 18 years+ - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Chicago, IllinoisAges 40–60 - NCT06477588Recruiting
HIV services and job help for justice-involved Black men
This study helps Black men who have sex with men or other key populations who have been involved with the justice system get HIV services and job support. It aims to connect you to care and employment help, especially if you aren't already receiving HIV or PrEP care.
Chicago, IllinoisAges 18 years+ - NCT07342491RecruitingPhase 1
Testing dasatinib to shrink HIV reservoir
This trial tests whether the drug dasatinib can reduce the hidden HIV reservoir in people who have had their virus well-controlled on HIV medications for a long time. It may help move toward a cure by targeting the cells where HIV hides.
Chicago, IllinoisAges 18 years+ - NCT06880705Recruiting
Trans-Led Care Study for alcohol and drug support
This study is testing a program designed by and for transgender adults to help with alcohol or drug use problems. It looks at whether a supportive, community-based approach can improve health and well-being.
Chicago, IllinoisAges 18 years+ - NCT06894199Recruiting
Work2Prevent Plus: Helping young Black men into HIV care
This trial tests a program called Work2Prevent Plus, which aims to help young Black men who have sex with men get into HIV care by connecting them with job support. If you're 18-29, identify as Black or African American, and have had sex with another man, you may be eligible.
Chicago, IllinoisAges 18 years+ - NCT07202546RecruitingPhase 2
New oral HIV drug trial for people new to treatment
This trial tests a new oral HIV medication (VH4524184) in people who have never taken HIV treatment before. It looks at how well the drug controls the virus and how safe it is.
Chicago, IllinoisAges 18 years+ - NCT06139224Recruiting
Gut Bacteria and Inflammation in HIV and Heavy Drinking
This study looks at how gut bacteria and inflammation interact in people with both HIV and heavy alcohol use. It aims to find new ways to improve health by understanding these connections.
Chicago, IllinoisAges 45–75 - NCT07392372RecruitingPhase 1
Testing the safety of BNT351 in people with and without HIV
This trial tests a new antibody called BNT351 to see if it is safe and how it affects the immune system. It is for adults who either do not have HIV, or have HIV and are not currently on HIV medications.
Chicago, IllinoisAges 18–65 - NCT06144229Enrolling by invitation
HPV Vaccine in Women with HIV
This study looks at how well the HPV vaccine works in women living with HIV and whether it helps make cervical cancer screening more accurate. If you are a woman with HIV between 21 and 40 years old and already part of certain other HIV studies, you may be able to join.
Chicago, IllinoisAges 21–40 - NCT07293559Recruiting
Understanding infant feeding choices in women with HIV
This study looks at how women with HIV decide whether to breastfeed, and what support they get from healthcare providers and family. It aims to learn about their experiences and needs.
Chicago, IllinoisAges Any age - NCT06266416Recruiting
Black caregivers & girls empowerment study
This study tests a program called IMARA to support black male caregivers and the girls they care for. It aims to improve family relationships and reduce risky behaviors in girls.
Chicago, IllinoisAges 13 years+ - NCT06206564RecruitingPhase 2
Artesunate ointment for anal precancer in HIV-negative adults
This trial tests an artesunate ointment to treat high-grade anal precancer (HSIL) in people who do not have HIV. The goal is to see if the ointment can clear the abnormal cells caused by HPV.
Chicago, IllinoisAges 18 years+ - NCT02140255RecruitingPhase 1/Phase 2
Intensive early HIV treatment in newborns to aim for remission
This study gives very early, intensive HIV medicine to infants diagnosed with HIV and follows them closely to see if HIV can go into remission (stop being detectable without ongoing treatment). It may help families understand whether treating right after birth can change a child’s long-term HIV outlook.
Chicago, IllinoisAges Up to 2 days - NCT05678556Recruiting
Relationship education to help prevent HIV in gay and bisexual men
This trial tests a relationship education program to help reduce HIV risk by supporting safer sex choices. It is for people who are currently at higher risk and are HIV-negative.
Chicago, IllinoisAges 16–34
Hear when a new HIV trial opens near Chicago, IL
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HIV trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting hiv studies listed above.
- University of Chicago · 3 studies
- Ann & Robert H. Lurie Children's Hospital of Chicago · 2 studies
- Howard Brown Health · 2 studies
- Northwestern University · 2 studies
- Rush University Medical Center · 2 studies
- 32515, Rush Univ./Cook County Hosp. Chicago CRS
- 4001, Lurie Children's Hospital of Chicago Clinical Research Site
- 5083, Rush University Cook County Hospital Clinical Research Site
What taking part in a hiv study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting hiv studies in Illinois.
Common questions
- Are there hiv clinical trials near Chicago?
- Yes. We're currently tracking 27 recruiting hiv studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a hiv study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New hiv studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.