Clinical trials · Raleigh–Durham, NC
HIV clinical trials in Raleigh–Durham
We’re tracking 14 recruiting hiv studies with a site in or near Raleigh–Durham — including Phase 1, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT06638892Recruiting
PrEP study for Black cisgender women
This study tests ways to help Black cisgender women take PrEP, a daily pill that prevents HIV infection. It focuses on making PrEP work for you.
Durham, North CarolinaAges 18 years+ - NCT06627764Recruiting
Family support program for Latino families with teens
This study tests a family-based program to help Latino families with teenagers aged 12-17. The program addresses overlapping health and social challenges to improve family well-being.
Durham, North CarolinaAges 12–100 - NCT07719491RecruitingPhase 1
Study of GS-0415 in People with HIV
This study tests a new drug, GS-0415, for people with HIV. The study will see if this drug can help control the virus. Participants will continue taking their regular HIV medication.
Durham, North CarolinaAges 18–65 - NCT05075967Enrolling by invitation
Study attitudes and services among southern gay and bisexual men
This study gathers opinions and experiences from gay and bisexual men and from clinic staff in the American South. It helps researchers understand what affects HIV prevention and care, and how programs can better support people at higher risk.
Durham, North CarolinaAges 15 years+ - NCT07143968RecruitingPhase 2
Resmetirom for people with MASLD and HIV
This study tests if resmetirom can help people who have both HIV and a liver condition called MASLD (fat buildup in the liver not caused by alcohol). You may qualify if your liver has a certain amount of fat and stiffness, and your HIV is well controlled with stable medication.
Durham, North CarolinaAges 18 years+ - NCT05753683Recruiting
Online group talks to build social support for young women
This study tests whether online discussion groups can increase social support for young Black/African American women who have had recent substance use. It also specifically focuses on women who are HIV negative and not using PrEP, to support healthier choices and community connection.
Durham, North CarolinaAges 18–30 - NCT07218211RecruitingPhase 4
Injectable PrEP study for Latine transgender women and gay men
This study offers a long-acting injectable form of PrEP (lenacapavir) to prevent HIV in Latine transgender women and gay men in the South. It aims to make HIV prevention easier by providing a shot instead of a daily pill.
Durham, North CarolinaAges 18 years+ - NCT07596888RecruitingPhase 1
Early safety study of experimental HIV treatment IAP-086-1
This is an early-stage trial testing a new experimental drug (IAP-086-1) in people with HIV who have their virus well-controlled on current medications. Researchers want to understand how safe the drug is and how the body handles it.
Durham, North CarolinaAges 18–70 - NCT07202546RecruitingPhase 2
New oral HIV drug trial for people new to treatment
This trial tests a new oral HIV medication (VH4524184) in people who have never taken HIV treatment before. It looks at how well the drug controls the virus and how safe it is.
Durham, North CarolinaAges 18 years+ - NCT05129345Recruiting
HIV care program for heart health goals in the Southeast US
This trial tests an approach to help people living with HIV reach heart- and metabolism-related health goals, such as blood pressure, cholesterol, and blood sugar. It involves clinics and community partners and may offer education, support, and care coordination to remove barriers to treatment.
Durham, North CarolinaAges 18 years+ - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Chapel Hill, North CarolinaAges 40–60 - NCT05241990Recruiting
Help improve alcohol care for people with HIV in clinics
This study tries a practical clinic strategy to help HIV clinics better offer and carry out alcohol treatment. You may be able to join if you work at the clinic or if you have HIV and your alcohol use screening shows possible unhealthy drinking.
Chapel Hill, North CarolinaAges 18 years+ - NCT07216794RecruitingPhase 2
Alendronate trial to reduce hidden HIV
This study tests if alendronate, a bone-strengthening medicine, can shrink the reservoir of HIV that stays in your body even when on treatment. You must have well-controlled HIV on antiretroviral therapy for at least one year but no more than ten years, and meet specific health requirements.
Chapel Hill, North CarolinaAges 18–65 - NCT07755618Enrolling by invitationPhase 1
Doxycycline levels and adherence study
This study looks at how the antibiotic doxycycline stays in your body and how well people stick to taking it. It may help find better ways to prevent infections.
Chapel Hill, North CarolinaAges 18–65
Hear when a new HIV trial opens near Raleigh–Durham, NC
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HIV trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting hiv studies listed above.
- Duke Early Phase Clinical Research Unit · 2 studies
- Duke University School of Nursing · 2 studies
- University of North Carolina · 2 studies
- 3201 Chapel Hill CRS
- Chapel Hill CRS
- Duke University - Duke Study Site
- Duke University Medical Center
- El Centro Hispano
What taking part in a hiv study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting hiv studies in North Carolina.
Common questions
- Are there hiv clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 14 recruiting hiv studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a hiv study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New hiv studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.