Clinical trials
Hyperpigmentation clinical trials
Below are recruiting hyperpigmentation clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07769268Recruiting
Cream for treating dark spots on the face
This study tests a cosmetic cream to reduce dark spots on the face, including melasma and sun spots. It aims to see if the product improves the appearance of hyperpigmentation.
Osasco, São PauloAges 30–60 - NCT05362929Recruiting
Laser treatment for acne scars in darker skin tones
This study tests a new type of laser treatment for acne scars in people with darker skin tones. It aims to see if the laser is effective and safe for improving the appearance of scars.
Elmsford, New YorkAges 18 years+ - NCT07195539Enrolling by invitation
Laser and medicine for burn scar darkening
This trial tests if combining a special laser with a skin-lightening medicine can safely reduce dark marks from old burn scars.
Lahore, Punjab ProvinceAges 18–60 - NCT06253468Recruiting
A cream for dark spots from sun, melasma, or acne
This study tests a new cream for facial dark spots caused by sun damage, melasma, or acne. It aims to see if the cream is safe and effective over three months.
SingaporeAges 18 years+ - NCT06268496Recruiting
Study of a cream for facial dark spots
This trial tests a skincare formula for treating three types of dark spots on the face: melasma, acne marks, and age spots. It aims to see if the product is effective and gentle after 3 months of daily use.
OsascoAges 18 years+ - NCT07067879Recruiting
Lip product with seaweed extract for lip darkening
This study tests a new lip product made with a seaweed extract (Caulerpa lentillifera) to see if it can reduce darkening of the lips. If you have lip hyperpigmentation and want to try a natural option, this may be a good fit.
BangkokAges 18–60 - NCT06149780Recruiting
Laser treatment for dark spots after inflammation
This trial tests a special laser to see if it can safely lighten dark spots that appear after skin inflammation, especially in people with darker skin tones. It may help if you have these spots and they bother you.
Detroit, MichiganAges 18 years+ - NCT07410156Recruiting
Comparing treatments for dark gums
This trial tests a new technique using tiny needles and a plant extract (silymarin) to lighten dark gums, and compares it to laser and scalpel methods.
Al FayyumAges 18 years+ - NCT07402720Recruiting
Brush vs bur for gum color treatment
This trial compares two methods to lighten dark gums caused by melanin: a polishing brush and a ceramic bur. It will help find which works better and is safer for people with gum pigmentation.
CairoAges 18–40 - NCT07513727Recruiting
Vitamin C Treatment for Dark Gum Pigmentation
This study tests whether vitamin C can safely lighten dark spots or patches on your gums that are caused by natural pigmentation. If you're bothered by how these dark areas look, this trial may help improve your smile's appearance.
Cairo, Cario GovernorateAges 20–40 - NCT07679945Recruiting
Study of facial sunscreen for dark spots
This study tests whether a facial sunscreen can reduce dark spots and pigmentation after 8 weeks of daily use. It may be a good option if you have age spots, melasma, or other dark marks on your face and want a simple, non-invasive treatment.
Campinas, São PauloAges 18 years+ - NCT07595705RecruitingPhase 2
Testing gum pigmentation removal treatments
This study tests treatments to lighten dark spots or patches on your gums for cosmetic reasons. If you have visible brown or black discoloration on your gums and are interested in a minor procedure to improve their appearance, this trial may be for you.
Al Fayyum, Faiyum GovernorateAges 18 years+ - NCT07618572Recruiting
Cosmetics and Self-Esteem in Black Women with Skin Darkening
This study tests whether special cosmetic products can help improve dark marks on the skin (post-inflammatory hyperpigmentation) and boost self-esteem and quality of life in Black women. You'll use the cosmetics regularly and answer questions about how you feel.
São Paulo, São PauloAges 18–55 - NCT07136766Enrolling by invitationPhase 3
Test cream vs prescription cream for dark spots on face
This study tests a new cream against a standard prescription cream (4% hydroquinone) to treat dark spots or melasma on the face. You will use a cream daily and avoid other skin treatments for about 4 months.
Teaneck, New JerseyAges 18–75
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Common questions
- Are there clinical trials for hyperpigmentation?
- Yes. Clin2 currently lists 14 recruiting hyperpigmentation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperpigmentation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperpigmentation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.