Clinical trials
Intracanal Medication clinical trials
Below are recruiting intracanal medication clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06566508RecruitingPhase 2/Phase 3
Gotu kola gel for root canal infections
This study tests a natural gel made from asiaticoside (a compound from the Gotu kola plant) placed inside your root canal after cleaning. This gel may help reduce infection and inflammation better than standard medicines.
Al MansurahAges 20–60 - NCT07641933RecruitingPhase 1
Root Canal Retreatment Dressing Comparison Study
This study compares different medicines placed inside root canals between appointments to help heal infections. You'll have a tooth retreated (cleaned and filled again) and help researchers find which dressing works best.
CairoAges 21–45 - NCT06453304RecruitingPhase 2/Phase 3
Licorice root gel for root canal infection
This trial tests a natural anti-inflammatory medicine called glycyrrhizin (from licorice root) used inside the tooth during root canal treatment. It aims to see if it helps kill bacteria and reduce infection better than standard medications.
Al MansurahAges 20–60 - NCT07256561Recruiting
Testing simvastatin gel inside root canals for infection and pain
This study tests whether a gel containing simvastatin, a medicine usually used for cholesterol, can help fight infection and reduce inflammation inside a tooth's root canal. It might be a treatment option for people who have a failed root canal and still have a small infection at the tip of the tooth root.
CairoAges 20–40 - NCT06207253RecruitingPhase 2/Phase 3
Testing diclofenac gel for tooth root infections
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
CairoAges 18–50 - NCT07141459Recruiting
Laser disinfection for failed root canal treatment
This trial tests if using a special laser (810 nm diode) to disinfect the tooth after a second root canal treatment can reduce pain and inflammation. It aims to help patients whose previous root canal failed and who have a small infection around the tooth root.
CairoAges 20–40 - NCT06196515RecruitingPhase 2/Phase 3
Study of a new nano-medication for infected tooth root canals
This trial tests whether a nano-scale calcium hydroxide paste works better than standard treatments for tooth infections. If you have a permanent molar with signs of infection around the root tip, this study may be an option.
CairoAges 21–49 - NCT06466538RecruitingPhase 2/Phase 3
Boswellia vs standard medicine for root canal infection
This trial tests whether a natural gum resin (Boswellia) placed inside the tooth during root canal treatment can fight infection better than standard medications. It may be a good option for people with a single-rooted tooth infection who are otherwise healthy.
Al MansurahAges 20–60 - NCT06533215Recruiting
Nano gel for root canal retreatment in infected premolars
This study tests a new, nano-sized antimicrobial gel to fight stubborn infections during repeat root canal treatment. It's for people with a premolar that still hurts or shows signs of infection after a previous root canal.
TantaAges 19–60 - NCT07075055Recruiting
New bioceramic medication for infected front teeth
This trial tests a new bioceramic medication placed inside the root canal of infected front teeth to see if it improves healing. It is for adults with mature front teeth and an infection around the root tip, who are otherwise healthy.
MinyaAges 18–40 - NCT07571837Recruiting
Nano-medication to reduce inflammation after root canal retreat
This study tests a special nano-sized (extremely tiny) medication placed inside a tooth after a previous root canal treatment failed. The goal is to reduce inflammation and swelling in the bone around the tooth's tip so it can heal better.
Cairo, Nasr CityAges 20–40
Hear when a new Intracanal Medication trial opens
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Common questions
- Are there clinical trials for intracanal medication?
- Yes. Clin2 currently lists 11 recruiting intracanal medication studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intracanal medication trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intracanal medication trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.