Testing simvastatin gel inside root canals for infection and pain
Part of Infections clinical trials.
This study tests whether a gel containing simvastatin, a medicine usually used for cholesterol, can help fight infection and reduce inflammation inside a tooth's root canal. It might be a treatment option for people who have a failed root canal and still have a small infection at the tip of the tooth root.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 40 years old.
- You had a root canal treatment before that did not work, and now you have pain or infection.
- The affected tooth has only one root, and the infection at the tip is between 2 mm and 8 mm on an x-ray.
- You are not pregnant, and you have no allergies to simvastatin or other trial medicines.
- The tooth can still be fixed (it is not broken or too damaged), and you do not have advanced gum disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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