Clinical trials
Migraine Disorders clinical trials
Below are recruiting migraine disorders clinical trials, each written for real people, not researchers. We’re tracking 47 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06623188Recruiting
Ear stimulation for treating episodic migraine
This trial tests if a device that gently stimulates the ear can reduce migraine attacks. It is for adults with regular migraines who have not had success with at least two preventive medications.
MarseilleAges 18–60 - NCT04939922Recruiting
Headache and dizziness registry for people with headache disorders
This study is a registry, meaning it collects information over time about people with headaches (including migraine, tension-type, and some dizziness-related headaches). It may help researchers better understand these conditions and plan future studies.
Hangzhou, ZhejiangAges 4–99 - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT05334927Recruiting
Headache disorder registry for teens and adults with primary headaches
This study is a headache disorder registry that enrolls people with common, “primary” headache types such as migraine or tension headache, including some with medication-overuse headaches. It collects information to better understand these conditions and who they affect.
Anqing, AnhuiAges 12 years+ - NCT06796725Recruiting
Study of TMS for migraine guided by brain imaging
This study tests whether repetitive transcranial magnetic stimulation (rTMS), guided by magnetoencephalography (MEG), can help people with frequent migraines or tension-type headaches. If you have headaches 15 or more days per month, this treatment might reduce your pain.
ShanghaiAges 15–50 - NCT07163416Recruiting
Italian migraine registry study for adults
This study tracks people with migraine to learn more about their condition and improve care. You may join if you have episodic or chronic migraine, with or without aura or medication overuse headaches.
Roma, RomaAges 18 years+ - NCT05669703Recruiting
Tracking mood and activity patterns in bipolar disorder families
This study watches how a person’s mood and movement change over time, and how those patterns relate to bipolar disorder. It may help researchers better understand the condition in families and potentially improve future care.
Bethesda, MarylandAges 8–70 - NCT05690737Recruiting
Tai chi program to prevent episodic migraine
This trial tests whether a tai chi routine can help prevent episodic migraine attacks and reduce bothersome symptoms like nausea or light/sound sensitivity. It also looks at how tai chi may change the brain or body processes involved in migraine.
Hong Kong, HONG KONGAges 18–65 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT04748601RecruitingPhase 4
Qudexy XR to help prevent migraine in kids ages 6 to 11
This study tests whether Qudexy XR can reduce migraine headaches in children ages 6 to 11. It looks for kids who are having frequent, disruptive migraine attacks and checks safety with careful medication rules.
Birmingham, AlabamaAges 6–11 - NCT07348783Recruiting
Yoga for chronic migraine and cluster headache
This study tests whether yoga-based movements can help reduce headache frequency and improve well-being in people with chronic migraine or cluster headache. You would follow online or in-person yoga instructions at home for several weeks, wear an activity tracker, and provide blood samples.
HuddingeAges 18–65 - NCT06503848Recruiting
Migraine attack treatment response biomarkers study
This study looks at how your body responds to migraine attack treatment, by tracking symptoms and blood markers. It may help find better ways to treat migraines in the future.
BarcelonaAges 18–45 - NCT07571889Recruiting
Numbing spray to reduce Botox injection pain for chronic migraine
This study tests whether a numbing spray applied inside the nose before Botox injections can reduce injection pain in people with chronic migraine. The goal is to make the treatment more comfortable without affecting how well it works.
East Providence, Rhode IslandAges 18 years+ - NCT06464367RecruitingEarly Phase 1
Psilocybin study for migraine and healthy volunteers
This study looks at how psilocybin affects the brain in people with migraines and in healthy volunteers. The goal is to understand why it may help with headache disorders.
West Haven, ConnecticutAges 21–70 - NCT05342493Recruiting
Survey study of long-term Ajovy injections
This is a study that collects information about how people use Ajovy (a medication for migraine) over time by injection. It mainly looks at safety and real-world use, and it may help researchers understand long-term treatment needs.
OsakaAges 18 years+ - NCT07514208Enrolling by invitation
Headache Sensitivity and Pain Testing Study
This study examines how sensitive the skin and tissues around the head are in people with migraines or tension headaches. Researchers will perform gentle touch and pressure tests to understand pain patterns, which may help improve headache treatment in the future.
Barcelona, BarcelonaAges 18 years+ - NCT07720765Recruiting
Using eye scans to study brain diseases
This trial uses a type of eye scan (OCT) to look at the retina in people with brain conditions like multiple sclerosis, Alzheimer's, Parkinson's, or migraines. It aims to see if these scans can help doctors learn more about the disease and monitor it over time.
Milan, MilanoAges 18 years+ - NCT06309251Recruiting
Ketogenic diet for children with epilepsy or other conditions
This trial studies how well a ketogenic diet works for children with hard-to-treat epilepsy or certain other diseases. It aims to see if the diet improves quality of life.
Milan, MIAges Up to 18 years - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19 - NCT06665867Recruiting
Video Follow-Up for Kids With Stomach Pain
This trial tests whether video consultations (video calls) are a good option for follow-up appointments in children with functional abdominal pain disorders. It aims to make check-ups easier for families.
AmsterdamAges 4–17 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+
Hear when a new Migraine Disorders trial opens
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Common questions
- Are there clinical trials for migraine disorders?
- Yes. Clin2 currently lists 47 recruiting migraine disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.