Clinical trials
Pneumococcal Vaccines clinical trials
Below are recruiting pneumococcal vaccines clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07242092RecruitingPhase 4
Pausing methotrexate to boost pneumonia vaccine response
This study tests whether stopping methotrexate for a short time before getting the pneumonia vaccine (PCV20) helps your body build a stronger immune response. It is for people with autoimmune rheumatic diseases like rheumatoid arthritis or lupus whose disease is under control.
São Paulo, São PauloAges 18–100 - NCT04460235RecruitingPhase 4
Compare two pneumococcal vaccines in adults treated for lymphoma
This trial compares two vaccination plans to see which one works better for preventing pneumococcal infections after lymphoma chemotherapy. You may be randomly assigned to one of the vaccine strategies, and the study checks your immune response.
AngersAges 18 years+ - NCT06514547RecruitingPhase 4
Vaccine response and aging in people with HIV
This study is for people living with HIV who are 18 or older and on HIV medication. Researchers want to learn how the immune system and vaccine response change as people age, and will give a pneumococcal (pneumonia) vaccine to study that.
Minneapolis, MinnesotaAges 18 years+ - NCT07406334RecruitingPhase 1
Pneumococcal booster vaccine study for toddlers
This trial tests a new pneumococcal vaccine as a booster shot in toddlers who already got a full primary series. It aims to see if the booster is safe and produces a strong immune response.
Soweto, Johannesburg, GautengAges 1 year–1.3 years - NCT07252791RecruitingPhase 4
PCV20 vaccine study for kids and young adults with rheumatic diseases
This study tests if a pneumonia vaccine (PCV20) is safe and works well in children and young adults with certain autoimmune rheumatic diseases like juvenile arthritis, lupus, or dermatomyositis. It aims to help protect them from serious infections.
São Paulo, São PauloAges 2–25 - NCT06760208Recruiting
Learning about Prevenar 20 in the real world in Korea
This study is for people who are already getting the Prevenar 20 vaccine (a shot that protects against pneumonia and other infections) as part of their regular care. The researchers want to see how well it works in the real world, so it's a simple way to help improve vaccines for everyone.
SeoulAges 1 month+ - NCT02232191RecruitingPhase 2
Pneumonia vaccine immune response study after spleen injury
This trial studies how your immune system responds to a pneumonia (pneumococcal) vaccine after a spleen injury. It may help doctors better predict and improve protection in people recovering from splenic trauma.
Sacramento, CaliforniaAges 18–65 - NCT05452941Recruiting
Pneumonia vaccine study for hospitalized adults 65 and older
This study tests a pneumococcal vaccine designed for 20 types of bacteria in older adults who are hospitalized with suspected community-acquired pneumonia. It aims to see how the vaccine works in real-world care and whether it affects how pneumonia happens or progresses.
El Centro, CaliforniaAges 65 years+ - NCT07135427RecruitingPhase 4
Genes and vaccines in alpha-1 antitrypsin deficiency
This study looks at how genetic differences in alpha-1 antitrypsin deficiency affect immune response to a pneumonia vaccine. It may help find better ways to prevent lung infections.
Birmingham, AlabamaAges 19 years+ - NCT07247188RecruitingPhase 3
Pneumococcal vaccine study for children with sickle cell disease
This trial tests a single dose of a new pneumococcal vaccine (21-valent) in children and teens with sickle cell disease. It aims to see if the vaccine can help protect against serious infections caused by pneumococcus bacteria, which are especially dangerous for people with SCD.
Atlanta, GeorgiaAges 2–17 - NCT03942328RecruitingPhase 1/Phase 2
Immune cell vaccine plus checkpoint treatment after liver radiation
This trial tests a combination of a personalized immune cell treatment (made from your own cells) and a pneumococcal vaccine along with an “immune checkpoint” drug after high-dose radiation for certain unresectable liver cancers. The goal is to help your immune system better attack the cancer and to see how safe and effective this approach is.
Rochester, MinnesotaAges 18 years+ - NCT07205289RecruitingPhase 1
Blood sample study for vaccine test development
This study collects blood samples to help researchers develop better tests. It is for healthy people who have not had a pneumococcal vaccine before.
Adelaide, South AustraliaAges 18–69 - NCT06822907RecruitingPhase 4
Testing pneumococcal vaccine during a fever in adults
This trial tests if a pneumococcal vaccine (PCV-20) is safe and works well when given to adults during a fever. It may help protect people with certain health conditions from serious pneumococcal infections.
Saint-Etienne, FranceAges 18–85
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Common questions
- Are there clinical trials for pneumococcal vaccines?
- Yes. Clin2 currently lists 37 recruiting pneumococcal vaccines studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pneumococcal vaccines trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pneumococcal vaccines trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.