Clinical trials
PPROM clinical trials
Below are recruiting pprom clinical trials, each written for real people, not researchers. We’re tracking 9 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05773014Recruiting
Digital versus speculum exams for leaking pregnancy fluid
This study compares two ways of checking the cervix (a finger exam versus a speculum exam) in people with PPROM, which is when the water breaks early. It looks at whether one exam method is more comfortable or practical after the rupture has happened.
St Louis, MissouriAges Any age - NCT02997345Recruiting
PPROM pregnancy registry for women under 37 weeks
This registry is collecting information from pregnant people diagnosed with preterm premature rupture of membranes (PPROM) before 37 weeks. It may help researchers better understand PPROM and improve care for future patients.
Denver, ColoradoAges 14–55 - NCT04047849RecruitingPhase 4
Antibiotics for early water breaking before 23 weeks
This trial studies whether taking antibiotics can help in pregnancies where the “water” broke early (before 23 weeks) but you don’t have a fever. It aims to reduce complications while keeping both mother and baby as safe as possible.
Baton Rouge, LouisianaAges 18 years+ - NCT07669207RecruitingPhase 4
Extended azithromycin for early water breaking
This study tests whether giving the antibiotic azithromycin for a longer period can help prevent infections in pregnant people whose water breaks early (between 22 and 28 weeks). If you are staying in the hospital for monitoring, this treatment aims to keep you and your baby healthier for as long as possible before delivery.
Pittsburgh, PennsylvaniaAges Any age - NCT07559071Recruiting
Emotional Freedom and Music Therapy for High-Risk Pregnancy
This study tests whether emotional freedom technique (a tapping-based stress-relief method) and music therapy can help reduce anxiety in pregnant women diagnosed with preterm premature rupture of membranes (PPROM)—a condition where the amniotic sac breaks early. The goal is to see if these therapies improve emotional well-being during a stressful pregnancy situation.
Konya, KonyaAges 18 years+ - NCT07183462RecruitingPhase 4
Antibiotic treatment for late preterm water breaking
This trial tests whether a combination of two antibiotics (azithromycin and ampicillin) can help pregnant people whose water has broken between 34 and 36 weeks of pregnancy. The goal is to see if this treatment improves outcomes for both the parent and baby without causing early labor or infection.
Ramat Gan, IsraelAges 18–50 - NCT07119398RecruitingPhase 4
Comparing two ways to start labor after water breaks early
This trial tests if adding a Foley bulb to oxytocin is better than oxytocin alone for inducing labor when your water has broken early (between 34 and 37 weeks). It aims to find the safest and most effective method to help you deliver.
Norfolk, VirginiaAges 18–50 - NCT07107477RecruitingPhase 3
Tailored therapy for preterm membrane rupture to prolong pregnancy
This trial tests a personalized treatment plan for people whose water breaks too early (before 34 weeks). The goal is to safely extend the pregnancy and improve health outcomes for both the parent and baby, while reducing the use of antibiotics.
BrnoAges 18 years+ - NCT06396078RecruitingPhase 4
Antibiotics for Early Water Breaking Before Delivery
This study tests whether giving antibiotics to pregnant people with early water breaking (PPROM) before delivery improves outcomes. It aims to prevent infections and protect both parent and baby while waiting for delivery.
Columbus, OhioAges 18 years+
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Common questions
- Are there clinical trials for pprom?
- Yes. Clin2 currently lists 9 recruiting pprom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pprom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pprom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.