Clinical trials
PrEP Adherence clinical trials
Below are recruiting prep adherence clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05762705Recruiting
Mobile game app to help you take PrEP
This trial tests whether a mobile gaming app can help people stick with PrEP (HIV prevention) so doses aren’t missed. It may help you stay on track during the first month after starting or restarting PrEP.
Boston, MassachusettsAges 15–34 - NCT06158607Recruiting
PrEP adherence help for women with substance use
This study tests a program to help Black and Hispanic women with substance use disorders take PrEP consistently to prevent HIV. The goal is to see if talking with a health coach can improve PrEP use and reduce HIV risk.
Houston, TexasAges 18–60 - NCT07186244Recruiting
HIV Prevention Study for People Starting or Taking PrEP
This study is for people who are HIV-negative and want to take PrEP (a daily pill that prevents HIV). It will help researchers learn more about how to best support people taking PrEP in real-world settings.
Chieti, AbruzzoAges 18 years+ - NCT06919614RecruitingPhase 3
Testing STIs to Improve PrEP Use in Pregnancy
This trial tests whether STI testing during pregnancy helps more women start and stay on PrEP (a daily pill that prevents HIV). If you join, you'll help find better ways to protect both mother and baby from HIV.
GaboroneAges Any age - NCT07509827Recruiting
App-based program to help prevent HIV and reduce stigma
This study tests a mobile health program to help young transgender women prevent HIV and cope with stigma. Participants use an app and are not yet taking PrEP daily or have trouble sticking with it.
Bangkok, BangkapiAges 18–29 - NCT07002866Recruiting
PrEP access and adherence study for young women in Uganda
This study tests a program to help adolescent girls and young women at high risk of HIV take PrEP consistently. It aims to improve access and adherence to PrEP, a daily pill that prevents HIV.
St Louis, MissouriAges 15–24 - NCT06558825Recruiting
PrEP support for women with trauma history
This study tests a program to help women who have experienced trauma and are at risk for HIV start and stay on PrEP (a daily pill that prevents HIV). It looks at whether mental health treatment can boost PrEP use.
Houston, TexasAges 18 years+ - NCT05736614Recruiting
Helping men who have sex with men take PrEP consistently
This trial tests ways to improve how well people take PrEP (a medicine that helps prevent HIV) consistently. It may help you if you’re at higher risk and are not currently on PrEP, especially around starting and staying on it.
Los Angeles, CaliforniaAges 18 years+ - NCT06880224Recruiting
HIV prevention and treatment for Nigerian youth aged 15-24
This study tests better ways to find and treat HIV in young people (ages 15-24) in Nigeria. It offers either HIV prevention medicine (PrEP) if you are HIV-negative, or HIV treatment if you are newly diagnosed with HIV.
Uyo, Akwa Ibom StateAges 15–24 - NCT06872307Recruiting
Helping Black men stay on PrEP
This study tests a new way to help Black men who have sex with men stay on PrEP (HIV prevention pills) over time. If you are at risk for HIV and have stopped taking PrEP for at least a month, you may be able to join and get support to keep taking it.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05624931Recruiting
Helping pregnant women stay on PrEP after starting it
This study tries to reduce the psychological barriers that make it hard for pregnant or postpartum women to keep taking PrEP. It may help by offering support tailored to stress, trauma symptoms, or depression—especially soon after PrEP is started.
Boston, MassachusettsAges 15 years+
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Common questions
- Are there clinical trials for prep adherence?
- Yes. Clin2 currently lists 11 recruiting prep adherence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prep adherence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prep adherence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.