Clinical trials · California
Substance Use Disorders clinical trials in California
We’re tracking 33 recruiting substance use disorders studies with a site in California — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07021352Recruiting
Ear acupuncture for emotional distress in military with PTSD
This trial tests whether ear acupuncture can help active-duty service members and veterans who have emotional distress related to PTSD. You will also receive mindfulness therapy as part of the study.
Fairfield, CaliforniaAges 18–65 - NCT07433985Recruiting
California mobile app study for men after jail release
This study tests a mobile app to help men recently released from jail or prison who use drugs or have sex with men stay healthy and avoid HIV. It's for people who don't have HIV and live in certain California counties.
Oakland, CaliforniaAges 18–59 - NCT05541406Recruiting
School support program for LGBTQ high school students
This trial is testing a program designed to make high schools more supportive for LGBTQ students. It aims to see if the program improves the school experience and well-being of LGBTQ youth.
El Monte, CaliforniaAges 12–20 - NCT06387290RecruitingPhase 3
Mindfulness and pain management for chronic pain on opioids
This study tests whether adding mindfulness training to standard pain management visits can help people with chronic pain who are taking long-term opioids. It aims to improve pain relief and reduce opioid-related risks.
La Jolla, CaliforniaAges 18 years+ - NCT06617312RecruitingPhase 2
Cytisinicline and brain response to smoking cues
This study tests how a medicine called cytisinicline (similar to a plant-based stop-smoking aid) affects brain activity when you see or think about smoking. It may help researchers understand how the medicine works, even if you aren't ready to quit right now.
Los Angeles, CaliforniaAges 18–65 - NCT06494891RecruitingPhase 2
Understanding motivation for IV alcohol drinking
This study looks at why people with alcohol use disorder choose to drink alcohol given through an IV. The goal is to better understand the motivation behind drinking, which could help improve treatments.
Los Angeles, CaliforniaAges 21–65 - NCT05619185Recruiting
Online program to help couples reduce risky drinking
This study tests an adaptive (tailored) online program to help service members and their partners cut down risky alcohol use. It also focuses on whether couples can practice healthier communication and coping skills while feeling safe together.
Palo Alto, CaliforniaAges 18 years+ - NCT05598034Recruiting
Brain stimulation with tDCS for moderate depression
This study tests whether a noninvasive brain stimulation called tDCS can improve depression symptoms. It also uses MRI scans, aiming to understand how brain changes may relate to symptom improvement.
Los Angeles, CaliforniaAges 20–55 - NCT07763392Recruiting
Normal cognitive test scores for adults
This study is testing a voice-controlled digital platform to measure normal memory and thinking abilities in healthy adults. By participating, you would help create a baseline of normal scores that doctors can use to compare against when assessing people with thinking problems.
Carlsbad, CaliforniaAges 18–100
Substance Use Disorders trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting substance use disorders studies listed above.
- University of California, Los Angeles · 2 studies
- Anderson W. Clark Magnet High School
- Animo Leadership High School
- Animo Pat Brown Charter High School
- Arroyo High School
- Blair High School
- Brio College Prep
- CAL-PEP
What taking part in a substance use disorders study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Substance Use Disorders trials in other states
Common questions
- Are there substance use disorders clinical trials in California?
- Yes. We're currently tracking 33 recruiting substance use disorders studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a substance use disorders study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a substance use disorders trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New substance use disorders studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.