Clinical trials · Texas
Substance Use clinical trials in Texas
We’re tracking 13 recruiting substance use studies with a site in Texas — including Phase 1, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Texas
- NCT06158607Recruiting
PrEP adherence help for women with substance use
This study tests a program to help Black and Hispanic women with substance use disorders take PrEP consistently to prevent HIV. The goal is to see if talking with a health coach can improve PrEP use and reduce HIV risk.
Houston, TexasAges 18–60 - NCT07281261Recruiting
Nerve stimulation for alcohol use disorder
This study tests whether a mild nerve stimulation device (tAN) can help reduce alcohol cravings and withdrawal. It's for people with moderate to severe alcohol use disorder who are going through withdrawal and do not use tobacco.
Houston, TexasAges 18–64 - NCT07218549RecruitingPhase 1
Study of psychoactive substances in people with past opioid use
This trial tests how safe certain psychoactive substances are and what effects they have in people who have used opioids in the past but are not currently dependent on them. It aims to gather information that could help future treatment options.
Houston, TexasAges 18–55 - NCT04811014RecruitingPhase 4
Helping young adults stop opioids after an emergency visit
This study offers an engagement program for young people who tested positive for opioids and meet criteria for opioid dependence. The goal is to help participants stop opioid use safely and learn whether this approach works well in the real-world emergency setting.
Houston, TexasAges 13–17 - NCT06424184Recruiting
Fast brain stimulation for addiction and depression
This study tests a quick, non-invasive brain stimulation method (rTMS) to help people who use stimulants like cocaine or methamphetamine and also feel depressed. The goal is to see if it can reduce cravings and improve mood.
Dallas, TexasAges 18–65 - NCT06679062RecruitingPhase 2
Suvorexant for alcohol use disorder and PTSD
This study tests whether the sleep medication suvorexant can help people with both alcohol use disorder and PTSD. If you're struggling with drinking, PTSD symptoms, and poor sleep, this trial may offer a new treatment option.
Houston, TexasAges 21–65 - NCT06074354Recruiting
MY-RIDE app for HIV prevention and substance use in homeless youth
This study tests a smartphone app called MY-RIDE to help homeless youth prevent HIV and reduce substance use. The app sends helpful tips at the right time to support healthier choices.
Houston, TexasAges 18–25 - NCT04366531Recruiting
Support for veterans after prison release
This study tests a program to help veterans with mental health or substance use issues transition from prison back into civilian life. It may provide support to improve reintegration and reduce the risk of returning to prison.
Dallas, TexasAges 18 years+ - NCT07741825Recruiting
Mindfulness training to prevent relapse for peer support workers
This study tests a mindfulness-based program to help people who work as peer support specialists in substance use recovery reduce their risk of relapse. It may help you manage cravings and stay healthy in your role.
Austin, TexasAges 18–100 - NCT06558825Recruiting
PrEP support for women with trauma history
This study tests a program to help women who have experienced trauma and are at risk for HIV start and stay on PrEP (a daily pill that prevents HIV). It looks at whether mental health treatment can boost PrEP use.
Houston, TexasAges 18 years+ - NCT07387796Recruiting
Brain and behavior changes with tirzepatide stop and restart
This study looks at how your brain and behavior change when you stop and then restart the weight loss drug tirzepatide. It will help researchers understand what happens during treatment breaks.
Dallas, TexasAges 18–70 - NCT07223398Recruiting
Making HIV care decisions with people who've been in the justice system
This trial helps people recently involved with the justice system and who use stimulants or opioids decide on HIV prevention or treatment. It tests a shared decision-making approach for taking HIV medication (ART) or PrEP.
Dallas, TexasAges 18 years+ - NCT07097376Recruiting
Job counseling for veterans with mental health and substance use issues
This trial tests a vocational counseling program to help unemployed veterans with mental health or substance use disorders find and keep meaningful paid work. You'll meet weekly with a counselor to build skills and support your return to employment.
Dallas, TexasAges 18 years+
Substance Use trials by city in Texas
Where these studies are running in Texas
Institutions with a site for the recruiting substance use studies listed above.
- Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston · 2 studies
- The University of Texas Health Science Center at Houston · 2 studies
- VA North Texas Health Care System Dallas VA Medical Center · 2 studies
- Addiction Research Institute
- Center for BrainHealth
- Michael E. DeBakey VA Medical Center
- Texas Christian University's (TCU) School of Medicine
- The Menninger Clinic
What taking part in a substance use study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Substance Use trials in other states
Common questions
- Are there substance use clinical trials in Texas?
- Yes. We're currently tracking 13 recruiting substance use studies with a site in Texas, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a substance use study in Texas?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Texas to take part?
- Not necessarily. These studies have a site in Texas, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a substance use trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New substance use studies open in Texas regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.