Clinical trials
Third Molars Extraction clinical trials
Below are recruiting third molars extraction clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07824518Recruiting
Comparing two bone graft materials after wisdom tooth removal
This study compares two types of bone graft material used to help healing after removing impacted lower wisdom teeth. It tests whether a graft made from your own tooth works as well as one from a cow (bovine xenograft).
Madrid, MadridAges 18 years+ - NCT07742826Recruiting
Platelet-rich fibrin vs. steroids after wisdom tooth removal
This study compares two treatments to reduce pain and swelling after removing an impacted wisdom tooth: one uses a special blood clot (platelet-rich fibrin) placed in the socket, and the other uses steroid medication. The goal is to find which works better for healing and comfort.
NicosiaAges 18 years+ - NCT07511816RecruitingPhase 2
Pain Relief Study After Wisdom Tooth Removal
This study tests a new pain medication (LY4515100) in people recovering from wisdom tooth extraction surgery. The goal is to see if it reduces pain better than current options after the procedure.
Salt Lake City, UtahAges 18–40 - NCT06778590Recruiting
Comparing two ways to remove lower wisdom teeth
This study compares two methods for removing lower wisdom teeth before they are fully grown. It uses a special ultrasound tool (piezoelectric) versus traditional surgical tools to see which is gentler and leads to faster healing.
CatanzaroAges 14–24 - NCT06864884RecruitingEarly Phase 1
Study of ARC-001 for wisdom teeth removal
This trial tests a new medicine called ARC-001 in people who are scheduled to have their wisdom teeth taken out. The goal is to see if it's safe and how it affects pain and healing.
Salt Lake City, UtahAges 18–55 - NCT07273968Recruiting
Virtual reality for anxiety during wisdom tooth extraction
This study tests whether wearing a virtual reality headset during wisdom tooth removal can help reduce anxiety. It is for generally healthy adults who are having multiple wisdom teeth extracted.
StrasbourgAges 18–65 - NCT07247929Recruiting
Pain and swelling after third molar surgery
This trial compares two surgical methods for removing partially impacted wisdom teeth to see which causes less pain and swelling afterwards.
Islamabad, IslamabadAges 18–45 - NCT07108465RecruitingEarly Phase 1
Anesthetic comparison for wisdom tooth removal
This trial compares two numbing medicines, bupivacaine and ropivacaine, to see which works better for removing impacted lower wisdom teeth during general anesthesia. It may help determine which option provides better pain relief after surgery.
Porto Alegre, Rio Grande do SulAges 18–60 - NCT07198282Recruiting
Comparing gum closure methods after wisdom tooth removal
This study compares two different ways of closing the gum after removing an impacted wisdom tooth. The goal is to see which method leads to less pain, swelling, and faster healing.
Rize, Rize ProvinceAges 18–40 - NCT07296926Recruiting
Numbing injection comparison for wisdom tooth removal
This study compares two numbing methods for removing a lower wisdom tooth. One is an injection near the tooth and the other is a nerve block. It aims to see which works better and may be more comfortable.
IslamabadAges 18–45 - NCT07180498Recruiting
Tea tree vs chlorhexidine mouthwash after wisdom tooth removal
This study compares a tea tree oil mouthwash and a standard chlorhexidine mouthwash to see which helps better after wisdom tooth removal. It may help you heal faster and with less discomfort.
SanliurfaAges 18–65 - NCT04880707RecruitingPhase 2
Pain medication options for lower wisdom tooth removal
This study compares pain-medication approaches during and after removing at least one lower impacted wisdom tooth (a tooth that’s stuck). It may help find a safer or more effective way to control dental pain after surgery.
Newark, New JerseyAges 18 years+ - NCT07803510Recruiting
Pictures before wisdom tooth surgery to reduce stress
This study tests whether showing patients pictures of their surgery before it happens can lower their stress, measured by a stress hormone in saliva. It may help you feel calmer about having your lower wisdom tooth removed.
Al Mansurah, AddakahlyiaAges 18–32 - NCT06953440RecruitingPhase 4
Dexamethasone injection for wisdom tooth surgery recovery
This trial tests if injecting dexamethasone (a steroid) into the gum after removing lower wisdom teeth can reduce swelling and difficulty opening your mouth. It may help you recover more comfortably after surgery.
Jeddah, Mecca RegionAges 18–65 - NCT06806241Recruiting
Tranexamic Acid Rinse for Wisdom Tooth Removal
This trial tests rinsing the surgery area with a medicine called tranexamic acid to see if it helps reduce bleeding and swelling after wisdom tooth removal. If you need both of your lower wisdom teeth out, this study might help your recovery.
Istanbul, FatihAges 14–40 - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT06539741Recruiting
Ibuprofen response study for wisdom tooth removal
This study looks at how people respond to ibuprofen after having one or more impacted wisdom teeth removed. It aims to understand why pain relief varies between individuals.
Philadelphia, PennsylvaniaAges 18 years+ - NCT01805869Recruiting
Teeth removal study using leftover tissue for research
This study looks at people who need wisdom tooth (third molar) removal and collects the leftover tissue after extraction. The goal is to use these samples to help dental research, while making sure the procedure can be done safely.
Bethesda, MarylandAges 16–50 - NCT04860141RecruitingPhase 4
Gabapentin before wisdom tooth removal to reduce pain
This trial tests whether taking gabapentin before extracting a wisdom tooth helps with pain and comfort after the procedure. It may help people who need a third-molar removal, if they meet the safety and health requirements.
Loma Linda, CaliforniaAges 18–59 - NCT06741696Recruiting
Saline rinsing after wisdom tooth removal
This trial tests whether using saline (salt water) at different temperatures after wisdom tooth surgery helps with healing and pain. It could help you recover more comfortably.
Rawalpindi, Punjab ProvinceAges Up to 59 years
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Common questions
- Are there clinical trials for third molars extraction?
- Yes. Clin2 currently lists 20 recruiting third molars extraction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a third molars extraction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a third molars extraction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.