Clin2
NCT07244029Possibly a fitRecruiting

Herbal extract for pain and swelling after wisdom tooth surgery

Postoperative PainFacial SwellingTrismus

Treatments studied

Part of Brain & nervous system, Pain clinical trials.

This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
18 years to 40 years
Study type
Interventional

Who can take part

  • You need to have an impacted wisdom tooth in your lower jaw that needs to be surgically removed.
  • You must be between 18 and 40 years old.
  • You must be generally healthy with no serious medical conditions.
  • You cannot have taken painkillers, steroids, or antibiotics in the 3 weeks before surgery.
  • You must not be pregnant or breastfeeding.
  • You cannot have allergies to aescin, ibuprofen, or any anesthetics used.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07719270Not yet recruiting
Pain relief after wisdom tooth removal

This study tests three ways to reduce pain and swelling after removing a lower wisdom tooth. It compares a steroid injection, kinesiology taping, and standard care to see which works best.

Lahore, Punjab Province
NCT07554963Not yet recruiting· Phase 4
Steroid injection to reduce pain after wisdom tooth surgery

This trial tests whether injecting a steroid (dexamethasone) into the gum before removing a lower wisdom tooth reduces pain, swelling, and discomfort after surgery. It may help you recover more comfortably after your procedure.

NCT06237231Not yet recruiting· Phase 3
New painkiller for wisdom tooth extraction pain

This study tests a new painkiller for people who have moderate to severe pain after having impacted wisdom teeth removed. If you qualify, you may receive the study drug or a placebo to see if it safely reduces pain better than no treatment.

NCT06539741Recruiting
Ibuprofen response study for wisdom tooth removal

This study looks at how people respond to ibuprofen after having one or more impacted wisdom teeth removed. It aims to understand why pain relief varies between individuals.

Philadelphia, Pennsylvania
NCT07269171Not yet recruiting
Enzyme supplements after lower wisdom tooth removal

This study tests whether taking extra supplements (enzymes that may reduce swelling and pain) after wisdom tooth removal helps you heal faster and feel better. If you're having an impacted lower wisdom tooth taken out, this trial may offer added support for your recovery.

Ankara
NCT07511816Recruiting· Phase 2
Pain Relief Study After Wisdom Tooth Removal

This study tests a new pain medication (LY4515100) in people recovering from wisdom tooth extraction surgery. The goal is to see if it reduces pain better than current options after the procedure.

Salt Lake City, Utah

Hear when a new Postoperative Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.