Clinical trials
Trauma clinical trials
Below are recruiting trauma clinical trials, each written for real people, not researchers. We’re tracking 407 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05588791Recruiting
Whole-body CT in the ER to spot low-risk trauma patients
This study looks at whether doing a whole-body CT scan in the emergency room can help identify adults who are at low risk after a road accident or fall. It may help doctors decide who can be managed with less intensive testing or monitoring.
RouenAges 18 years+ - NCT05638581RecruitingPhase 3
Compare low-titer type O whole blood for trauma bleeding
This study tests whether giving low-titer type O whole blood (or related blood products) works better for treating serious bleeding after a traumatic injury. It’s for adults who start blood transfusions right away under a massive bleeding plan.
Birmingham, AlabamaAges 15 years+ - NCT05683132Recruiting
Therapy to improve sleep in women with PTSD symptoms
This study is testing treatment approaches for improving insomnia (trouble sleeping) in women Veterans who also have PTSD symptoms. It may help reduce sleep problems and improve day-to-day functioning.
West Los Angeles, CaliforniaAges 18 years+ - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT05700201Recruiting
Study of heart health in adults with trauma symptoms
This study looks at how trauma-related symptoms (like PTSD symptoms) may affect heart health. You may be asked to do light activity—so your study team can see how your body responds.
Fort Lauderdale, FloridaAges 18 years+ - NCT05701254Recruiting
Study how type 1 diabetes affects fracture risk bones
This study compares bone structure in women with type 1 diabetes versus women without diabetes, to understand why fractures can happen more easily. You may need blood tests, scans, and a small bone biopsy (a surgical sample from your hip/thigh area).
Omaha, NebraskaAges 50 years+ - NCT05721378Recruiting
Testing safer walking weight on a surgically treated heel fracture
This trial studies whether “permissive weight bearing” (walking with allowed weight) is safe and helpful after surgery for a displaced heel bone fracture. It’s meant to improve recovery while protecting the healing bone.
AmsterdamAges 18–67 - NCT05725499Recruiting
Check if skin stimulation lowers blood pressure drops after spinal injury
This study tests a skin “stimulation” treatment to see if it helps stabilize blood pressure in people with spinal cord injury who get low blood pressure when sitting up. If you often have dizziness, faintness, or low readings after changing positions, this trial may help find safer ways to manage it.
West Orange, New JerseyAges 18–75 - NCT05731986Recruiting
Skin nerve stimulation to raise blood pressure after spinal injury
This study tests whether a device that delivers mild electrical stimulation through the skin can improve low blood pressure after an acute spinal cord injury. It may help reduce episodes of dizziness or faint-feeling caused by blood pressure dropping when you sit up.
West Orange, New JerseyAges 18–75 - NCT05765864Recruiting
Study of self-harm in at-risk teens
This study looks at self-harm and thoughts/behaviors related to safety in teenagers who are considered at higher risk. It may help researchers better understand what supports are needed for teens who self-harm without wanting to die.
LjubljanaAges 13–18 - NCT05816083Recruiting
Virtual reality tool for teens and young adults after trauma
This study tests a virtual reality program to help young people who have been through serious violence or sexual assault (“ITE”). It’s also open to certain healthcare workers who support these young people.
Charleston, South CarolinaAges 15–30 - NCT05846321Recruiting
Registry for blood vessel injury after trauma follow-up
This study keeps a registry of adults with injuries to blood vessels caused by trauma and tracks follow-up outcomes. Your participation may help doctors better understand how these injuries heal and how to manage them.
AugsburgAges 18 years+ - NCT05855252Recruiting
Study on monitoring and outcomes after moderate to severe head injury
This observational study follows adults with moderate to severe traumatic brain injury to understand care and outcomes. It collects information from the first 48 hours in the ICU and may help improve how clinicians monitor and treat patients in the critical early period.
Kogarah, New South WalesAges 18 years+ - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT05889559Recruiting
Testing a fluid drainage method to detect leg pressure problems
This study looks at a special drainage measurement (“tissue ultrafiltration”) to better detect and treat acute compartment syndrome, a dangerous increase in pressure in the leg after major injury. It may help doctors identify who needs urgent treatment and improve outcomes after severe leg fractures or crush injuries.
Baltimore, MarylandAges 18–60 - NCT05942469Recruiting
Online study for emotion skills to prevent secondary trauma
This study tests an online program to help people regulate their emotions, aiming to reduce “secondary trauma” from their work. You may be able to join if you meet the simple eligibility needs below.
Chicago, IllinoisAges 18 years+ - NCT05964140RecruitingPhase 3
Testing antibiotics after jaw fracture surgery
This trial studies whether giving (or how giving) antibiotics affects outcomes after surgery for a broken lower jaw (mandible). It may help reduce infection risk and antibiotic-related side effects if the right approach is chosen for the right patients.
Blackburn, LancashireAges 18 years+ - NCT05964764Recruiting
Check which head-injury guidelines work for children
This study tests and confirms Swedish/Norwegian guidelines for treating minor to moderate head injuries in children. It may help doctors decide the safest next steps after an injury, especially for whether and when to use scans and observation.
HaukelandAges Up to 17 years - NCT05976256Recruiting
Kinesio tape for new shoulder or chest injuries
This trial looks at whether kinesio tape (elastic therapeutic tape) helps pain and movement after a fresh shoulder or chest wall injury. It’s designed for certain types of rib, collarbone, or shoulder joint injuries when the injury happened very recently.
AmsterdamAges 18 years+ - NCT06033027Recruiting
Testing a soft robotic glove for hand help
This trial tests a soft robotic glove that helps you grip and hold objects if your hand is weak due to a nerve problem or injury. It's meant for people who have trouble with daily tasks like eating or dressing.
Enschede, OverijsselAges 18–90 - NCT06043453Recruiting
Revitalizing injured, growing permanent teeth
This trial tests a new approach to help injured, still-growing permanent teeth heal and continue to develop naturally. It may be an option if your child has a traumatized tooth with an infection and the root is not yet fully formed.
GhentAges 6–18 - NCT06048172Recruiting
Trauma therapy for PTSD with a psychotic disorder
This trial tests if prolonged exposure therapy, a common PTSD treatment, can help people who also have a psychotic disorder (like schizophrenia or bipolar with psychosis). The goal is to reduce PTSD symptoms.
HamburgAges 18 years+ - NCT06051227RecruitingPhase 3
Pain relief after injury: fentanyl vs. esketamine
This trial compares two strong pain medicines—fentanyl and esketamine—to see which works better for treating pain right after a traumatic injury. You would receive the medicine by spray in your nose or through a vein before going to the hospital.
AmsterdamAges 18 years+ - NCT06070350RecruitingPhase 3
Massive transfusion for life-threatening bleeding in children
This study tests whether adding the drug tranexamic acid (TXA) to a massive blood transfusion helps control life-threatening bleeding in children who are severely injured. It compares two groups: one gets TXA and the other gets a placebo (a dummy drug with no active ingredient).
Tucson, ArizonaAges Up to 17 years
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Common questions
- Are there clinical trials for trauma?
- Yes. Clin2 currently lists 407 recruiting trauma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a trauma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a trauma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.