Clinical trials
Vaginal Cancer clinical trials
Below are recruiting vaginal cancer clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06846775Recruiting
DNA test in urine and vaginal samples for endometrial cancer
This study tests if a DNA test in urine and vaginal samples you collect at home can help find endometrial cancer. It compares results from people with the cancer to healthy volunteers.
Aarhus NAges 60 years+ - NCT06649201Recruiting
Study of vaginal health after stem cell transplant
This study looks at how stem cell transplants affect the vagina, especially if you develop a condition called graft-versus-host disease (GVHD). Researchers will examine the vagina and test its natural germs (microbiome) to better understand and possibly improve treatment.
Cleveland, OhioAges 18–70 - NCT03422198RecruitingPhase 3
Short course vaginal radiation after hysterectomy
This trial tests a short course of targeted vaginal radiation (brachytherapy) after surgery for certain early endometrial cancer. It may help prevent the cancer from coming back in the vaginal area after the uterus has been removed.
Palo Alto, CaliforniaAges Any age - NCT05984875Recruiting
Immune system study for ovarian cancer
This study looks at how the immune system works in people with epithelial ovarian cancer. It aims to understand the immune landscape around the tumor, which could lead to better treatments in the future.
BellinzonaAges 18 years+ - NCT07217353Enrolling by invitation
Testing a new speculum for endometrial biopsies
This trial tests a new type of vaginal speculum designed to make endometrial biopsies (a procedure to take a small sample of the lining of the uterus) more comfortable and effective. If you have had this biopsy before at the Minnesota Oncology Clinic, you may be eligible to help evaluate this new tool.
Englewood, ColoradoAges 18–90 - NCT06254846Recruiting
Urine test for HPV cervical cancer screening
This study tests if a urine sample can replace a cervical swab for HPV testing during cervical cancer screening. If it works, it could make screening easier and less uncomfortable.
Saint-EtienneAges 30–65 - NCT04098744RecruitingPhase 2
Artesunate vaginal inserts for high-grade cervical changes
This Phase 2 study tests whether artesunate vaginal inserts can help treat high-grade abnormal cells on the cervix (CIN2/3). It’s meant for adults who have a confirmed high-grade precancer change and can use birth control during the study.
Fort Myers, FloridaAges 25–100 - NCT07527143Recruiting
DNA test for endometrial cancer using vaginal fluid
This study tests whether DNA markers in vaginal fluid can help detect endometrial cancer. You'll provide a sample and take part in a virtual interview.
Rochester, MinnesotaAges 45 years+ - NCT07407647RecruitingPhase 2
Vaginal DHEA for better vaginal health after pelvic radiation
This study tests whether a vaginal insert of DHEA (a hormone) can help with vaginal health problems caused by pelvic radiation for anal, rectal, or gynecologic cancers. It is for women who are already postmenopausal and are about to start radiation.
Columbus, OhioAges 50 years+ - NCT05857631Recruiting
After-surgery radiation schedule for cervical or uterine cancers
This trial studies a shorter, focused radiation schedule given after surgery for certain higher-risk cervical or endometrial (uterine) cancers. It may help reduce cancer recurrence while checking side effects in the bladder and bowel area.
Navi Mumbai, MaharahstraAges 18–80 - NCT07144826RecruitingEarly Phase 1
Probiotic for Gut and Vaginal Health in Ovarian Cancer Chemotherapy
This trial tests whether taking a probiotic supplement can help balance the bacteria in your gut and vagina while you undergo chemotherapy for advanced ovarian cancer. It aims to see if this could improve your treatment experience or outcomes.
Columbus, OhioAges 18 years+ - NCT06356012RecruitingPhase 4
Imiquimod for high-risk HPV cervical lesions
This trial tests if imiquimod cream can help clear high-grade cervical lesions caused by high-risk HPV. It may be an option for people who want to avoid surgery.
BarretosAges 25–45 - NCT06007027Recruiting
Vaginal laser therapy for breast cancer survivors with menopause symptoms
This trial tests whether a vaginal laser treatment can help breast cancer survivors who have menopause-like symptoms such as vaginal dryness or pain during sex. It is designed for women currently on hormone-blocking therapy.
RandersAges 18–100 - NCT07400835Recruiting
Using DNA markers to find endometrial cancer in postmenopausal bleeding
This trial tests whether DNA changes in urine, vaginal, or cervical samples can help find endometrial cancer earlier in women with postmenopausal bleeding. If you are having tests for this bleeding, your samples could help improve detection.
Aarhus NAges Any age - NCT06638931RecruitingPhase 2
Nivolumab for rare solid tumors with high PD-L1
This trial is testing a drug called Nivolumab (an immunotherapy) for people with rare solid tumors that have high levels of PD-L1. It might be an option if you have tried other treatments and they stopped working or caused too many side effects.
Fortaleza, CearáAges 18 years+ - NCT07622953Recruiting
Vaginal Fluid Markers for Early Detection of Gynecological Cancer
This study collects vaginal fluid samples to test whether certain biological markers (substances in the fluid) can help detect gynecological cancers earlier or track how they change during treatment. You may qualify if you're being evaluated for, currently receiving treatment for, or receiving comfort care for a gynecological cancer.
SouthamptonAges 18 years+ - NCT05255653RecruitingPhase 2/Phase 3
Personalized after-surgery treatment for endometrial cancer by tumor type
This trial studies which after-surgery (adjuvant) treatment works best when endometrial cancer is classified by specific tumor DNA/molecular features. You may be offered treatment based on the tumor results, aiming to improve outcomes and lower the risk of the cancer coming back.
TorontoAges 18 years+ - NCT03617133RecruitingPhase 2
MRI-guided radiation plus chemo for cervical cancer
This trial tests a more precise way to deliver radiation for locally advanced cervical cancer using MRI guidance during treatment, along with chemotherapy. It may help shrink tumors more effectively while aiming to reduce side effects by targeting the right areas.
ViennaAges 18–99 - NCT05256225RecruitingPhase 3
Adding Herceptin medicines to chemo for HER2-positive endometrial cancer
This Phase 3 trial tests whether adding Herceptin Hylecta or Phesgo to standard chemotherapy works better than chemotherapy alone for HER2-positive serous endometrial cancer or carcinosarcoma. It may help by improving how well treatment controls or shrinks the cancer.
Birmingham, AlabamaAges 18 years+ - NCT04717349Recruiting
Study collects health information for kids’ and teens’ gynecology concerns
This is a research study that gathers information about pediatric and adolescent gynecology conditions. It may help researchers better understand these issues by learning about symptoms, care, and outcomes—without requiring a specific treatment.
Bethesda, MarylandAges 1 day–100 years - NCT07217171RecruitingPhase 1
Study of EVOLVE104 for advanced bladder and squamous cell cancers
This trial tests an experimental drug called EVOLVE104 for people with advanced bladder cancer or certain types of squamous cell cancers. It aims to see if the drug is safe and if it can help shrink tumors.
Duarte, CaliforniaAges 18 years+ - NCT06694519Recruiting
Radiofrequency and exercise for pelvic floor issues after breast cancer
This trial tests whether radiofrequency therapy combined with exercise can help with pelvic floor problems like pain, urgency, or incontinence that some women have after breast cancer treatment.
Elche, Spain / ValenciaAges 18 years+ - NCT05969860RecruitingPhase 2
Home cancer treatment vs clinic treatment for advanced cancer
This Phase 2 trial compares giving certain standard cancer infusions at home versus in a clinic. It may help people avoid clinic visits while still receiving the same cancer treatment safely.
Jacksonville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for vaginal cancer?
- Yes. Clin2 currently lists 71 recruiting vaginal cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaginal cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaginal cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.