Clinical trials
Vulvodynia clinical trials
Below are recruiting vulvodynia clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05955313RecruitingPhase 2
Low-dose naltrexone for different types of vulvodynia pain
This Phase 2 study tests whether low-dose naltrexone can reduce pain from vulvodynia. It also looks at how well it works across different vulvodynia types, comparing to what participants are already doing for symptoms.
LublinAges 18–50 - NCT06999395Recruiting
Virtual program for pelvic pain with vestibulodynia
This study tests whether a virtual program can help reduce pelvic pain and improve sexual experiences in people with a specific type of pain called provoked vestibulodynia. It is a completely online program, so you can participate from home.
Kingston, OntarioAges 18 years+ - NCT07391241RecruitingPhase 2
Pudafensine for vulvar pain study
This trial tests a new medicine called pudafensine to see if it safely reduces pain in women with vulvodynia, a condition that causes pain when the vulvar area is touched.
BlackpoolAges 18–65 - NCT07553715Recruiting
Shock Wave Therapy for Vulvodynia Pain in Women
This study looks at whether a four-session shock wave therapy treatment helps women with vulvodynia (chronic vulva pain). You're eligible if you've already started this treatment and want to help researchers understand how well it works.
Nantes, NantesAges 18 years+ - NCT05343182Recruiting
Compare two surgical techniques for vestibular pain
This study compares two different surgery techniques for people with long-lasting, touch-triggered pain at the vaginal entrance (“vestibule”). You might be offered one of the surgical approaches and you’ll complete pain testing and follow-up measurements to see which technique works best.
Portland, OregonAges 18–80 - NCT06660212Recruiting
Pelvic health rehab study for women with pain
This study tests whether biomodulation therapy combined with pelvic floor rehabilitation can help women with certain types of pelvic pain. It is for premenopausal women who were born female and are experiencing provoked vestibulodynia (pain at the vaginal opening) with or without vaginismus (tightness).
Ottawa, OntarioAges 18 years+ - NCT06840314Recruiting
Vibration vs traditional therapy for painful sex
This trial compares a vibrating vaginal device to standard therapy for women with pain during sex. It aims to find a more effective and comfortable treatment option.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06865963Recruiting
Better diagnosis for provoked vestibulodynia pain
This study uses advanced lab tests to better understand a type of vulvar pain called provoked vestibulodynia, which is pain only when the area is touched. Researchers hope to find new ways to diagnose it more accurately.
Pavia, PaviaAges 18–50 - NCT07257029RecruitingPhase 2
Ketotifen Cream for Vulvar Pain
This trial tests a topical cream called ketotifen for treating a type of vulvar pain (secondary provoked vestibulodynia). The cream may help reduce pain at the vaginal opening, and you would apply it daily for several months.
Washington D.C., District of ColumbiaAges 18 years+ - NCT01829204Recruiting
Health study registry for vaginal conditions
This study is building a database (a secure record) to learn about vaginal/vulva conditions in women. You may be invited if you’re coming in for a routine women’s health visit or you’re being seen for a vaginal concern, and you can share information safely.
Midland, TexasAges 21–75 - NCT06472765Enrolling by invitation
Study of the Vaginal Ecosystem in Healthy Women
This study looks at the natural balance of bacteria and other factors in the vagina of healthy women. It aims to learn more about what a healthy vaginal ecosystem looks like.
Fullerton, CaliforniaAges 18–89 - NCT03541512Enrolling by invitation
Remote mindfulness classes for painful vulvar touch during sex
This study tests whether a remote mindfulness program (using Headspace) can reduce pain or discomfort from provoked localized vulvar pain (pain when touched during sex). You may be randomly assigned to the mindfulness program or another study condition.
Portland, OregonAges 18–100
Hear when a new Vulvodynia trial opens
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Common questions
- Are there clinical trials for vulvodynia?
- Yes. Clin2 currently lists 12 recruiting vulvodynia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vulvodynia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vulvodynia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.