Treatment
Lidocain clinical trials
We’re tracking 131 recruiting studies that include Lidocain, each written for real people, not researchers, below.
Recruiting studies
- NCT05955768Enrolling by invitation
Lidocaine in a cervical dilator to reduce removal pain
This study tests whether putting lidocaine (a numbing medicine) into a disposable cervical dilator can reduce pain during uterine device removal done with local anesthesia. If you’re eligible, your experience of pain is measured so researchers can compare comfort between study procedures.
Hangzhou, ZhejiangAges 18–65 - NCT06694714RecruitingPhase 4
Testing how long numbing medicine lasts on the nose
This study tests two different numbing medicines on the sides of the nose to see how long each lasts and which works better.
New York, New YorkAges 18 years+ - NCT05667987Recruiting
Lidocaine to help prevent pancreas inflammation after ERCP
This study tests whether giving lidocaine during an ERCP procedure can lower the risk of a painful complication called pancreatitis. If you’re scheduled for ERCP with a “never-treated” opening, this trial may see if lidocaine helps you avoid post-procedure pancreas inflammation.
ParisAges 18 years+ - NCT06057675RecruitingPhase 2
Tranexamic acid for nose reconstruction after Mohs surgery
This trial tests if tranexamic acid (a medicine that helps blood clot) reduces bleeding and bruising during nose reconstruction after skin cancer removal. It is for adults having a specific type of flap repair on their nose.
Nashville, TennesseeAges 18 years+ - NCT06910241RecruitingPhase 3
Lidocaine vs. Diphenhydramine for Stitches in ER
This trial compares two numbing medicines—lidocaine and diphenhydramine—to see which works better for stitching up cuts in the emergency room. It helps find the fastest, most comfortable option for people needing stitches.
Boynton Beach, FloridaAges 18 years+ - NCT07053176Enrolling by invitationPhase 4
Neck injection for dizziness linked to neck pain
This trial tests whether a local anesthetic injection in the neck (paravertebral lidocaine) can reduce dizziness that is related to neck pain or stiffness. It may help if your dizziness started along with neck pain, trauma, or limited movement.
Fara in Sabina, RietiAges 18–80 - NCT07205757RecruitingPhase 4
Lidocaine added to Custodiol for heart bypass surgery
This study tests whether adding lidocaine to the standard heart preservation solution (Custodiol) helps protect the heart during coronary artery bypass surgery. If you are scheduled for elective bypass surgery, this trial might be relevant to you.
Al FayyumAges 18 years+ - NCT07643298Recruiting
Lidocaine through feeding tube to reduce nausea after weight-loss surgery
This study tests whether delivering lidocaine (a numbing medication) through a feeding tube during weight-loss surgery can reduce nausea and vomiting afterward. You would receive this medication as part of the surgery procedure to see if it helps you feel better in recovery.
Yinchuan, NingxiaAges 18–65 - NCT07204691Recruiting
Hyaluronic acid lip filler with lidocaine study
This study tests a new hyaluronic acid filler with lidocaine for making lips fuller. It is for healthy adults with thin lips who want a noticeable improvement.
MölndalAges 18 years+ - NCT03984656RecruitingPhase 3
Nerve-block pain control during lung fluid drainage in ICU
This trial tests whether a specific pain-relief nerve block (given with numbing medicine) can make pleural drainage in the ICU more comfortable. It may help reduce pain during the procedure for people who are awake and breathing on their own.
AmiensAges 18 years+ - NCT04048278RecruitingEarly Phase 1
Lidocaine IV infusion for pancreatic cancer treatment
This early-phase study tests whether giving lidocaine through an IV infusion can help treat pancreatic cancer. It will enroll people with confirmed pancreatic cancer that can be measured on scans, including some cases discovered to have spread during surgery.
Chicago, IllinoisAges 18 years+ - NCT04192773RecruitingEarly Phase 1
Brain-scan study of IV lidocaine for tinnitus
This early study uses an MRI/brain scan to see how IV lidocaine affects brain activity in people with tinnitus, and also compares it with people without tinnitus or with different hearing patterns. It may help researchers understand whether lidocaine could change tinnitus signals in the brain.
Boston, MassachusettsAges 18 years+ - NCT04874038RecruitingPhase 3
Lidocaine infusions to prevent long-lasting pain after breast surgery
This Phase 3 study tests whether receiving lidocaine through an IV during breast surgery can lower the chance of ongoing pain afterward. If it works, it may help some people avoid chronic, surgery-related pain in the chest wall, shoulder, or arm.
Calgary, AlbertaAges 18–100 - NCT07672236RecruitingPhase 3
Comparing two mouth pain treatments for head and neck cancer patients
This trial tests a new mouthwash (BupiZenge) against a standard numbing medicine (lidocaine) for pain caused by mouth sores from radiation therapy. It may help you if you are about to start radiation for certain head and neck cancers.
CopenhagenAges 18–80 - NCT07274254RecruitingPhase 3
Lidocaine to reduce opioid use for sickle cell pain crisis
This trial tests if adding lidocaine to standard pain treatment can reduce the amount of morphine or oxycodone needed for a severe pain crisis or acute chest syndrome in sickle cell disease. It is for adults in the ICU who have already started opioid treatment within the last 72 hours.
BordeauxAges 18 years+ - NCT05010148RecruitingPhase 3
IV lidocaine after spinal fusion to reduce delirium and pain
This trial tests whether giving lidocaine through a vein after elective spinal fusion surgery can help prevent confusion (delirium) and reduce pain. It may help people recover more comfortably and think more clearly after surgery.
San Francisco, CaliforniaAges 60 years+ - NCT05193227RecruitingPhase 2
Slow-release lidocaine patch for pain after pelvic surgery
This Phase 2 study tests a slow-release form of lidocaine to reduce pain after surgery that uses a pelvic incision. If you’re having a qualifying pelvic operation, the study may help see whether this medication improves postoperative pain control.
Vancouver, British ColumbiaAges 19 years+ - NCT05737121RecruitingPhase 2
Study drug for bladder pain compared with lidocaine, heparin, or placebo
This Phase 2 trial tests VNX001 to see if it helps people with interstitial cystitis/bladder pain syndrome (IC/BPS) compared with its separate ingredients (lidocaine and heparin) or a placebo (inactive treatment). You may be eligible if you have had IC/BPS for months and recently had a moderate-to-severe bladder pain flare.
Escondido, CaliforniaAges 18 years+ - NCT06272461Recruiting
Comparing lidocaine vs. ketamine for colorectal surgery pain
This trial compares two pain-relief medicines (lidocaine vs. ketamine) given through an IV during open colorectal surgery. It aims to find which one works better to reduce pain after surgery.
NabeulAges 18–90 - NCT06304779Recruiting
Lidocaine for infection after emergency abdominal surgery
This trial tests if giving lidocaine continuously during and after emergency surgery for a hole or blockage in the gut can reduce lung problems and improve recovery. It may help patients with a serious belly infection who need quick surgery.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT06349668RecruitingPhase 3
Comparing spinal morphine and IV lidocaine for robotic kidney surgery
This trial compares two ways to manage pain during robotic-assisted kidney or ureter surgery: a spinal injection of morphine or an intravenous infusion of lidocaine. The goal is to see which method provides better pain relief and recovery.
KalmarAges 18 years+ - NCT06391125RecruitingPhase 3
Lidocaine for pain relief with penicillin shot for syphilis
This study tests if adding a numbing medicine (lidocaine) to a penicillin shot reduces the pain of the injection for people being treated for syphilis. If you are starting your first of three weekly penicillin shots, you may be able to join.
St Louis, MissouriAges 18 years+ - NCT06405776Recruiting
Lidocaine for pain and survival after bowel surgery in older adults
This study tests whether a drug called lidocaine, given during surgery, can help control pain after colon or rectal surgery and possibly improve long-term survival in older adults. The goal is to see if lidocaine offers better pain relief and recovery compared to standard care.
SichuanAges 60 years+ - NCT06451562Recruiting
Pain relief methods after scoliosis surgery
This trial compares two ways to manage pain after scoliosis surgery: numbing the area near the spine (regional anesthesia) or giving lidocaine through an IV. The goal is to see which method reduces the need for morphine after surgery.
Be’er Ya‘aqovAges 12–25
Common questions
- Are there clinical trials studying Lidocain?
- Yes. Clin2 currently lists 131 recruiting studies that include Lidocain, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Lidocain trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Lidocain an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Lidocain or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.