Study of genetic variants in cancer families
Part of Cancer, Genetic & congenital clinical trials.
This study looks at how a specific DNA genetic change (variant) runs within cancer families. It may help researchers better understand cancer risk and improve genetic testing and interpretation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 18 years old
- You must be part of a family being studied because of a known genetic variant found in a cancer-related diagnostic test
- For the main participant (index case): your variant must be from an approved gene list and classified in a specific way (class 3, 4, or hypomorphic class 5) by the study network
- For relatives: you must be a family member of the index case and included by the study team based on family relationships and cancer history
- All participants must sign written informed consent (selected relatives and the index case)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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