Clinical trials
Genetic Predisposition clinical trials
Below are recruiting genetic predisposition clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06584994Enrolling by invitation
Genetics and cancer risk in families
This study looks at how genes passed down in families might increase the chance of getting cancer. It collects samples from children with cancer and their family members to better understand cancer risks.
CambridgeAges Any age - NCT06089421Recruiting
Genetic information assistant for cancer risk testing
This study tests a tool called GIA (Genetic Information Assistant) that helps people understand genetic testing for cancer risk. You would use the tool on a smartphone or computer during a genetic counseling session.
Charlottesville, VirginiaAges 18 years+ - NCT07181213Enrolling by invitation
Genetic links to high blood pressure
This trial is for people who took part in a large study (SCAPIS) and have both a certain genetic trait and high blood pressure. The goal is to understand how your genes may affect blood pressure.
Linköping, Östergötland CountyAges 50 years+ - NCT04141462Recruiting
Genetic testing study for early cancer risk
This study looks at whether DNA (from a tumor or related samples) can help identify inherited cancer risk in people who develop cancer at a young age. It may help families learn more about risk factors and guide future screening or prevention.
BesançonAges 18 years+ - NCT05849155Recruiting
Talking study for teens with inherited cancer risk
This study looks at how parents and children communicate after learning about an inherited (genetic) cancer risk. It may help researchers find better ways to support families in these conversations.
Memphis, TennesseeAges 10–24 - NCT07456904Recruiting
Transition to adult care for cancer risk patients
This study looks at how young adults with a genetic risk for cancer (cancer predisposition syndrome) transition from St. Jude children's care to adult healthcare. It aims to understand their health outcomes and help improve future care.
Memphis, TennesseeAges 18 years+ - NCT03538639Recruiting
Study blood and tissue samples for vascular disease discovery
This study collects blood (and sometimes tissue samples) from people who may have vascular (blood vessel) problems and from certain pregnant participants. Researchers use the samples to better understand vascular disease and to help guide future research.
Bethesda, MarylandAges 2–100 - NCT06450171Recruiting
Multi-cancer early detection test for people at high risk
This study tests a blood-based multi-cancer early detection (MCED) screening test in people with a high risk of cancer due to inherited gene changes or strong family history. The goal is to see if this test can find cancer early.
Boston, MassachusettsAges 22 years+ - NCT05587439Recruiting
Study of inherited genetic risk in lung and related cancers
This study looks for inherited (family-passed) genetic changes that may raise the risk of lung cancer and related thoracic cancers. It may help people and families understand their genetic risk by collecting health information and sometimes specimens from patients and relatives.
Boston, MassachusettsAges 18 years+ - NCT06057181Recruiting
Helix research network for adults
This study is a research network that collects health information from adults to better understand health and disease. It is open to most adults who are willing to follow the study procedures.
Fort Wayne, IndianaAges 18 years+ - NCT04419896Enrolling by invitation
Patient registry for people who had genetic testing
This registry collects past and ongoing health and genetic testing information from adults who have had germline or other genetic/blood biomarker tests. It helps researchers learn patterns that may improve cancer care in the future.
Redding, CaliforniaAges 18 years+ - NCT06800599Enrolling by invitation
Cancer genetic risk assessment registry
This study collects information from people who receive genetic counseling for cancer risk. Joining the registry helps researchers learn more about cancer genetics and improve future care.
Bologna, ItalyAges Any age - NCT06523179Recruiting
Liver cancer risk study for people with fatty liver disease
This study looks at your risk of developing liver cancer (hepatocellular carcinoma) if you have a liver condition such as NAFLD or a related disease. It aims to improve how doctors predict who might be at higher risk, so they can offer better monitoring and care.
Milan, MilanoAges 45–75 - NCT05656261Recruiting
Genetic testing study for African Americans
This study looks at genetic markers (genes) related to kidney risk in Black/African American adults. It may help researchers better understand who is at higher risk and how genetics could guide future care.
St Louis, MissouriAges 18–90 - NCT07112287Recruiting
Germline testing for myeloid cancer risk
This trial studies whether certain inherited genes increase the risk of myeloid cancers or bone marrow failure. You will provide a DNA sample via a skin biopsy to look for these genetic changes.
Boston, MassachusettsAges 18 years+ - NCT03862365Recruiting
Study genetics in people with nerve pain
This study looks at genetic differences in people being checked for a common type of nerve problem called distal symmetric polyneuropathy (nerve damage that usually affects the hands and feet). By understanding genetics, researchers hope to learn more about why neuropathic (nerve) pain happens and how it may differ between people.
BergenAges 18–70 - NCT07228000Recruiting
Cancer screening and genetic services navigation for Black and Hispanic women
This study helps Black and Hispanic women ages 45-74 get both breast and colorectal cancer screenings and genetic services. It provides a navigator to guide you through the process.
Newark, DelawareAges 45–74 - NCT04760522Recruiting
Genetic testing plan for patients with unclear disease cause
This study helps decide treatment planning based on genetic testing for people whose disease cause is unclear but may be genetic. It’s meant to support a “genomic health” approach, where results guide next steps in care.
TübingenAges Any age - NCT05350761Recruiting
Study rare tumors and inherited cancer risk in families
This study looks at people who have rare or unusual cancers or who may have an inherited (family) risk for cancer. It helps researchers learn what genetic or other factors might be involved by collecting family history and medical records, including pathology slides.
Bethesda, MarylandAges Any age - NCT04046796Recruiting
Study genetics in identical twin who differ in symptoms
This study looks at DNA changes to explain why two identical (monozygotic) twins can have different symptoms. It may help clarify the cause of an unclear condition in one twin so the right diagnosis (and future treatment) can be found.
TübingenAges Any age - NCT04702321Recruiting
Study genetic risks for childhood cancer complications in Switzerland
This study looks at genetic factors to understand why some children who had cancer develop later complications. It uses stored samples and information from a Swiss biobank to help researchers identify higher-risk children.
GenevaAges Up to 21 years - NCT06003153RecruitingPhase 4
Gene and sugar response study with oral semaglutide
This study looks at how your genes affect your body's response to a diabetes medication called semaglutide. It may help people with slightly high blood sugar (pre-diabetes) understand why some respond better than others.
Boston, MassachusettsAges 18–65 - NCT04513054Recruiting
Genetic study for stress-related heart muscle weakness
This study looks for a possible inherited (genetic) reason some people develop Takotsubo cardiomyopathy after severe stress. If you’ve had this condition, the study may help explain why it happens and whether families could be at higher risk.
Aberdeen, AberdeenshireAges Any age - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65
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Genetic Predisposition trials by city
Studies with a site in or near these metro areas.
Genetic Predisposition trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for genetic predisposition?
- Yes. Clin2 currently lists 71 recruiting genetic predisposition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic predisposition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic predisposition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.