Hyperbaric oxygen treatment for severe traumatic brain injury
Treatments studied
Part of Brain & nervous system, Injuries & trauma clinical trials.
This Phase 2 trial studies whether breathing oxygen in a pressurized chamber can improve outcomes after a severe traumatic brain injury. It is mainly for people with very low consciousness levels soon after injury, with careful safety checks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 16 and 65 years old
- You have a severe traumatic brain injury with a Glasgow Coma Scale (GCS) score of 3 to 8
- A brain CT scan shows a concerning injury score (Marshall CT score over 1), or there was alcohol above 200 mg/dL (if your GCS is 7–8)
- You can start the first hyperbaric oxygen session within 8 hours of hospital admission (or within 14 hours if you need major surgery)
- Your injury is traumatic brain injury (not a penetrating head wound)
- You are not pregnant and do not have safety reasons you cannot receive hyperbaric oxygen
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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