Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,926 recruiting studies in this area right now.
By phase
- Not applicable9,333
- Phase 2766
- Phase 1554
- Phase 3512
- Phase 4338
- Phase 1/Phase 2299
- Phase 2/Phase 3124
Top conditions
- Stroke797
- Parkinson Disease394
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea143
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia136
- Mild Cognitive Impairment126
- Cerebral Palsy118
- Pain Management114
- Migraine108
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital122
- Assistance Publique - Hôpitaux de Paris108
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California653
- Massachusetts304
- New York294
- Texas267
- Florida263
- Maryland248
- Arizona208
- Alabama205
- Illinois183
- Pennsylvania176
Recruiting studies11,926 total
- NCT07875127Recruiting
Hand movement test for people with certain conditions
This study looks at how people with mild hand movement problems or Down syndrome perform a simple hand test. It may help doctors better understand and measure hand skills.
Rome, ItaliyAges 4–18 - NCT05780450Recruiting
Brain stimulation for long covid headaches and pain
This trial tests a safe, non-invasive brain stimulation technique (transcranial direct current stimulation, or tDCS) to see if it can reduce persistent headaches and chronic pain in people with long covid. If you have ongoing pain after a confirmed covid infection, this could offer a new way to find relief.
Paiporta, ValenciaAges 16 years+ - NCT04344262Recruiting
Testing a small dose muscle relaxant during general anesthesia
This trial studies whether a small dose of a muscle-relaxing medicine works safely for people having surgery under general anesthesia. You might be a candidate if you fit the age and surgical setup, and you don’t have certain health problems or medication issues.
Al MansurahAges 20–50 - NCT07166055Recruiting
Family dance therapy for children with motor disabilities
This study tests whether dancing with your family can help children with motor challenges move better and have fun. It aims to see if this kind of therapy is practical and enjoyable for children ages 3 to 14.
ValenciaAges 3–14 - NCT07874594Recruiting
Brain training to improve sleep after a first stroke
This study tests a treatment that may help reduce brain inflammation and improve sleep in people who have had a first stroke and now have trouble sleeping. It uses a non-invasive technique called remote ischemic conditioning, which involves brief, repeated cycles of a blood pressure cuff on the arm.
Chengdu, SichuanAges 18–80 - NCT07876908Recruiting
Magnetic brain therapy for older adults with hard-to-treat depression
This trial tests a new intensive magnetic brain treatment (SAINT) for older adults whose depression has not improved with standard treatments. It aims to see if this treatment can also help with memory concerns, which are common in this group.
Costa Mesa, CaliforniaAges 65 years+ - NCT05484245Recruiting
Ultrasound-guided surgery for brain tumors
This trial tests whether using ultrasound during surgery helps doctors remove brain tumors more precisely. It may be an option for people aged 18 to 80 with certain types of brain tumors that can be reached with ultrasound.
MoscowAges 18–80 - NCT07876570Recruiting
Predicting memory decline with brain and blood tests
This study follows older adults with normal memory, mild memory problems, or dementia over a year to see if brain scans and blood tests can predict who will get worse. It may help find early warning signs of Alzheimer's and other dementias.
Beijing, Beijing MunicipalityAges 50 years+ - NCT03545477Recruiting
Curved walking training for stroke, Parkinson's and hip fracture recovery
This study tests whether practicing walking in curved paths can help people recovering from a stroke, Parkinson's disease, or a recent hip fracture improve their balance and mobility. If you have one of these conditions and are in a rehabilitation program, this training might make everyday walking easier.
Lissone, Monza E BrianzaAges 18–90 - NCT03631628Recruiting
Mirror therapy with gentle nerve stimulation for stroke arm recovery
This study tests whether combining mirror therapy with mild electrical nerve stimulation can help improve arm and hand movement after a stroke. It may be an option if you can move your unaffected arm and have some shoulder and wrist movement on your affected side.
Hong Kong, Hong KongAges 50–85 - NCT05477680Recruiting
Measuring brain shift during brain tumor surgery
This study looks at how the brain may shift during surgery for certain brain tumors. The goal is to improve the accuracy of the navigation system so surgeons can remove tumors more precisely.
MoscowAges 18–80 - NCT07594119RecruitingPhase 3
Testing RAP-219 to reduce seizures in focal epilepsy
This study tests a new medication called RAP-219 to see if it can reduce seizure frequency in adults with focal epilepsy (seizures starting in one area of the brain). You'll take the medication alongside your current seizure drugs and track your seizures daily using an app.
Huntsville, AlabamaAges 18–75 - NCT07521319Recruiting
Wearable device guide for sleep apnea and insomnia
This study tests a wearable device that helps guide treatment for people who have both sleep apnea and insomnia. It may help improve your sleep quality and daytime symptoms.
Tainan, TaiwanAges 20–80 - NCT07875257Enrolling by invitation
Brain-based therapy for recovery after a left-side stroke
This study tests a new brain-computer system that helps people recovering from a stroke in the left side of the brain. It uses your thoughts to move a device, which may help improve arm and hand movement.
Buenos Aires, EscobarAges 18–65 - NCT07637669Recruiting
Smell and decision-making in people with HIV and substance use
This study looks at how smell and decision-making are affected in people living with HIV and/or substance use disorders. You may join one of four groups based on your HIV status and substance use history, and you will complete smell tests and computer tasks, with an optional MRI.
Baltimore, MarylandAges 18–65 - NCT06832761Recruiting
Lifestyle help for people with early memory concerns
This trial tests whether a lifestyle program can help people with mild memory problems (subjective cognitive decline or mild cognitive impairment) who also have at least two things that increase their risk for dementia, like high blood pressure or lack of exercise. If you're 50 or older and have these memory issues and risk factors, you may be able to join.
AmsterdamAges 50 years+ - NCT06985212Recruiting
Study of acid sphingomyelinase deficiency in children and adults
This study follows people with acid sphingomyelinase deficiency (ASMD) over time to learn more about how the condition changes. You won't get any new treatment, but your participation will help doctors better understand ASMD.
Paris, FranceAges 2 years+ - NCT07875335Enrolling by invitation
Traditional Chinese medicine added to standard care for moyamoya disease
This trial tests whether a traditional Chinese herbal formula (Fufang Tongluo Decoction) can improve outcomes when added to aspirin and atorvastatin for people with moyamoya disease, a condition that narrows brain arteries and increases stroke risk. The study aims to see if this combination reduces stroke risk and improves overall well-being.
Nanjing, JaingsuAges 18–60 - NCT07764718Recruiting
Brain stimulation for adults with drug-resistant epilepsy
This trial tests a new type of brain stimulation to find and treat the area causing seizures in adults whose seizures don't improve with medication. It is done during a standard monitoring procedure to help doctors better target treatment.
Durham, North CarolinaAges 18 years+ - NCT03019757Recruiting
Testing ways to tell dementia causes apart
This study looks at how to distinguish Alzheimer’s disease, Lewy body dementia, and Parkinson’s disease when someone has memory and thinking problems. It may help doctors choose the most accurate diagnosis and treatment path for the right condition.
Columbus, OhioAges 18 years+ - NCT06366724RecruitingPhase 2
Life Improvement Trial for ME/CFS
This trial tests a new treatment for ME/CFS (chronic fatigue syndrome) that includes symptoms like dizziness when standing. It uses a smartphone app to track your progress and aims to see if the treatment can improve your daily life.
Boston, MassachusettsAges 18–70 - NCT07444450RecruitingPhase 3
Study of salanersen for babies with SMA previously treated with gene therapy
This study tests a new medicine called salanersen in babies who have already received gene therapy for SMA. It aims to see if adding salanersen is safe and effective.
Flower Mound, TexasAges birth–7 months - NCT01906385RecruitingPhase 1/Phase 2
Recurrent brain tumor study testing rhenium nano-liposome
This early-phase study tests a drug made of tiny fat-like particles carrying rhenium for recurrent (coming back) high-grade glioma. It mainly checks safety and the highest tolerable dose, and it also looks for signs the treatment may slow tumor growth.
Manhasset, New YorkAges 18 years+ - NCT07111065RecruitingPhase 2
Fatty Acid Supplement for Dermatomyositis
This study tests whether taking a fatty acid supplement (omega-3) for 6 months can help reduce disease activity in people with dermatomyositis. Participants will also receive dietary coaching and have regular check-ups at the NIH to monitor their progress.
Bethesda, MarylandAges 18–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,926 recruiting neurology studies from the U.S. registry right now, out of 18,261 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.