Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,736
- Phase 2785
- Phase 1578
- Phase 3537
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke839
- Parkinson Disease429
- Multiple Sclerosis344
- Alzheimer Disease340
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris114
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts298
- New York292
- Florida273
- Texas269
- Maryland248
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania175
Recruiting studies12,404 total
- NCT00001215Enrolling by invitation
Understanding Genetic Lysosomal Storage Disorders
This study aims to understand genetic factors in lysosomal storage disorders—rare conditions where the body cannot break down certain substances. Researchers will collect information from patients with these disorders, their family members, and healthy volunteers to learn how these diseases develop and affect people over time.
Bethesda, MarylandAges 1 week–110 years - NCT00344331Recruiting
Testing blood and MRI markers for Niemann-Pick type C
This study measures biochemical (blood/biologic) markers and may use clinical evaluation and MRI to better understand Niemann-Pick disease type C. It could help improve how the condition is tracked and understood over time.
Bethesda, MarylandAges 1 day–120 years - NCT00029965Recruiting
Understanding rare storage diseases over time
This study follows people with rare genetic conditions (GM1, GM2, sialidosis, or galactosialidosis) that affect how the body breaks down certain substances in cells. Researchers track how these diseases progress to better understand them and potentially help future patients.
Bethesda, MarylandAges 1 day–100 years - NCT07613918Recruiting
Brain Blood Flow Monitoring in Critically Ill Children
This study measures how well blood flows to your child's brain while they're in the intensive care unit on a breathing machine. Understanding this flow may help doctors better care for critically ill children.
Madison, WisconsinAges 1 day–17 years - NCT06988124Recruiting
Dexamethasone for nausea after brain surgery
This trial tests whether a steroid called dexamethasone palmitate can prevent nausea and vomiting after brain surgery. It is for adults having a planned craniotomy under general anesthesia.
BeijingAges 18–65 - NCT06975423Recruiting
Walking Sensation Study for older adults
This study is for older adults who walk slowly and have some loss of feeling in their feet. Researchers want to see if a special walking test can help understand this better. You must be generally healthy and free of major medical issues or recent surgeries.
Gainesville, FloridaAges 65–95 - NCT06967051Recruiting
Smartphone test of pupil response after cannabis use
This study uses a smartphone app to measure how your pupils react to light after using cannabis. It aims to see if the app can detect recent cannabis use, which could help develop a quick, non-invasive test.
London, OntarioAges 21 years+ - NCT06941714Recruiting
How thinking hard affects balance in young adults
This trial looks at how doing mental tasks (cognitive load) affects your balance and stability. You stand and maybe do a simple thinking exercise while your balance is measured, to see if mental effort makes it harder to stay steady.
IslamabadAges 18–30 - NCT06928077Recruiting
Power wheelchair training for toddlers with motor delays
This study tests whether adding special visual cues (like lights or arrows) to a power wheelchair helps toddlers with motor delays learn to drive it. If your child is between 1 and 3 years old, can't walk on their own, and can reach for toys, they may be a good fit.
Taoyuan City, Taoyuan CountyAges 10 months–3.3 years - NCT06870552Recruiting
Brain stimulation study for language processing
This study uses a safe type of brain stimulation called TMS (transcranial magnetic stimulation) to learn how the brain processes language. It may help researchers understand language better, and you could contribute to that knowledge.
Columbia, South CarolinaAges 18–40 - NCT06858566Recruiting
Study of Kaligo app for kids with writing difficulties ages 6-11
This trial tests if a tablet-based app called Kaligo can help children ages 6-11 who struggle with handwriting. Your child may join if they have trouble writing and score above a certain threshold on a handwriting test.
BrestAges 6–11 - NCT06691490Recruiting
Brain activity and daily physical activity study
This study looks at how your brain's perception of effort is linked to how much physical activity you do. It uses EEG (a cap that records brain waves) and fMRI (an MRI that shows brain activity) to understand this connection.
La TroncheAges Any age - NCT06337136Recruiting
Baby movement study for newborns
This study will analyze the movement patterns of newborns in the hospital to help understand early development.
GarchesAges 1 day–2 weeks - NCT06254638Recruiting
Moveschool: Boosting physical activity during school
This trial tests a school-based program designed to increase physical activity levels during the school day for teenagers. It aims to see if adding more movement into the school routine can improve health and activity habits.
CáceresAges 11–16 - NCT05969483Recruiting
Test of an EEG device to monitor sedation in children’s ICU
This trial checks whether a special EEG sensor can reliably monitor sedation in children in the pediatric intensive care unit (PICU) who are on a ventilator. It may help the care team adjust sedation more safely and accurately.
PadovaAges 1 day–18 years - NCT05217043Recruiting
Study brain recordings to track how meanings are learned
This study uses long-term recordings from inside the brain to see how your brain (and computers) builds and changes meaning over time as learning happens. Your participation may help researchers improve how we monitor language and meaning in both humans and artificial systems.
Paris, FranceAges 18 years+ - NCT07791966Recruiting
Brain stimulation for chronic pain
This study tests a non-invasive brain stimulation technique to help people with chronic pain, specifically Complex Regional Pain Syndrome (CRPS), manage pain-related avoidance behaviors. It may help reduce pain and improve daily function.
Cleveland, OhioAges 18 years+ - NCT07132775Recruiting
Full-body electrical stimulation suit for spasticity and pain
This study tests a full-body suit that delivers gentle electrical pulses to help reduce muscle stiffness, spasms, and pain in people with conditions like multiple sclerosis, fibromyalgia, or other neurological problems. It may help with movement and comfort.
Chicago, IllinoisAges 18–75 - NCT07792655Recruiting
Hand therapy at home after stroke
This study tests a therapy program done at home using video calls to help improve hand function after a stroke. It may help you regain better use of your hand if you had a stroke at least 6 months ago.
Ann Arbor, MichiganAges 40–75 - NCT07791472Recruiting
Delirium and light: a pilot study on risk factors
This study looks at why some patients in intensive care develop confusion (delirium) and whether light exposure affects it. It may help improve care for older patients in the hospital.
LondonAges 50 years+ - NCT07707830Recruiting
Thyroid and body health assessment for adults with low thyroid function
This study looks at how an underactive thyroid (hypothyroidism) affects internal organs, muscles, and bones. It uses ultrasound and physical measurements to understand these effects, which may help improve care.
AndijanAges 18–59 - NCT07792746Recruiting
Sleep apnea markers and use of CPAP therapy
This study looks at whether certain markers in sleep apnea patients can predict how well they will stick with CPAP (a mask that helps you breathe at night). If you're newly diagnosed and about to start CPAP, this could help personalize your care.
MontpellierAges 18 years+ - NCT07582809Recruiting
Digital therapy app for long-term insomnia relief
This study tests a smartphone app called BELL-001 that delivers digital therapy to help people with insomnia sleep better. It looks at how safe and effective the app is over a long period, and may offer an alternative to sleep medications.
IncheonAges 19–75 - NCT06302348RecruitingPhase 3
Sepiapterin study for phenylketonuria
This study tests a new medicine called sepiapterin to see if it can help control blood phenylalanine levels in people with PKU. The trial aims to find a safe and effective dose for different age groups.
Indianapolis, IndianaAges Up to 9 years
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,187 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.