Testing skipping breast surgery or radiation for top responders
Part of Cancer, Skin clinical trials.
This trial studies whether some people with early-stage breast cancer who respond extremely well to hormone/chemo/targeted treatment can safely skip breast surgery and/or radiation. It aims to reduce side effects without increasing cancer risk in carefully selected patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have early-stage, one-breast (unicentric) invasive breast cancer without spread to distant organs
- You must be able to plan breast-conserving treatment (lumpectomy instead of mastectomy)
- Your cancer subtype must match one of the trial’s groups (HER2-positive, or triple-negative, or ER/PR-positive/HER2-negative)
- Your lymph node ultrasound must not show many suspicious nodes (and any suspicious ones may need biopsy)
- If you’re triple-negative or HER2-positive, your age must meet the trial’s lower age limits; if ER/PR-positive/HER2-negative, there are also specific score/tumor-size rules
- You should not be pregnant and should not have prior radiation that would prevent required treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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