Omitting endocrine therapy and radiation in low-risk breast cancer
Part of Cancer, Skin clinical trials.
This trial tests whether older women with very low-risk, hormone-positive breast cancer can safely skip endocrine therapy (hormone-blocking pills) and radiation after lumpectomy. It aims to maintain quality of life while keeping cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 60 years or older.
- You had a lumpectomy (breast-conserving surgery) for invasive breast cancer.
- Your tumor is ER-positive, PR-positive, and HER2-negative.
- Your tumor is 3 cm or smaller with no cancer in lymph nodes.
- Your tumor has a low recurrence risk based on Ki-67 (≤20%) or Oncotype DX (0-10).
- You either never started endocrine therapy, or stopped it within 6 months of starting.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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