After surgery chemo sprayed into the abdomen for high-risk colon cancer
Part of Cancer, Digestive system clinical trials.
This Phase 2 study tests whether spraying chemotherapy into the abdomen (through a small procedure) after colon cancer surgery can lower the chance the cancer comes back. It is meant for people with high-risk tumor features but who have had surgery and have no proven relapse yet.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (over 18) and can give written consent
- Your colon cancer was removed completely, with high-risk tumor features as defined by the study (such as perforation, stage T4, or certain spread to the peritoneum/ovaries)
- Your overall health is good (performance status 0–1)
- If you can become pregnant, you must use approved birth control during the study
- Tests before treatment show you have enough blood cells, normal enough kidney and liver function, and no heart failure symptoms beyond mild limits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way to give chemotherapy – as a fine mist sprayed directly into the belly during a short laparoscopy (keyhole surgery). It is for people whose stomach, pancreas, or colon cancer has spread to the lining of the belly, and who haven't had much chemotherapy before.
This Phase 1 trial tests PIPAC, a way to deliver anti-cancer medicine directly into the abdomen using a minimally invasive procedure. It is for people with peritoneal spread from certain cancers to see whether this approach is safe and potentially helpful.
This Phase 1 study tests a new way to deliver chemotherapy inside the abdomen (belly) using a pressurized aerosol during a procedure, along with standard blood (IV) chemotherapy. It may help people with advanced ovarian cancer whose tumors have not progressed but are not removable with surgery yet.
This trial looks at a way to give chemotherapy into the abdomen (through a small tube during laparoscopy) for certain stomach cancers. It aims to see whether this approach improves cancer control and surgical outcomes for people whose tumors can potentially be removed.
This trial tests a new way to deliver chemotherapy directly into the abdomen (called PIPAC) for people with cancer spread to the lining of the belly. It uses the drug mitomycin and is for patients who cannot have standard surgery or heated chemotherapy.
This trial tests a special chemotherapy delivery method called PIPAC (pressurized intraperitoneal aerosol chemotherapy) for ovarian cancer that has spread within the abdomen. The goal is to deliver cancer-fighting drugs more effectively directly to where the cancer is.
Hear when a new Peritoneal Carcinomatosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.