Oral wheat tolerance treatment for children with wheat allergy
Part of Immune system & allergy clinical trials.
This trial tests a supervised “oral tolerance induction” approach, which means giving carefully controlled wheat exposure to try to train the immune system to tolerate wheat. It’s designed for children who have confirmed IgE-mediated wheat allergy, aiming to reduce allergic reactions over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is between 2 and 16 years old
- Your child has a documented wheat allergy with a clear past allergic reaction to wheat
- You can show the allergy using one or more tests (skin test or blood wheat-IgE) and a positive supervised wheat challenge (with some exceptions)
- Your child is not on allergy “immunotherapy” (shots or under-the-tongue treatments) or other immune-targeting biologic medicines
- Your child does NOT have severe or hard-to-control asthma or other serious lung disease
- Your child has not had life-threatening wheat reactions in the last year requiring ICU, and does not have wheat-triggered exercise anaphylaxis or celiac disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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