Study wheat triggers in people with non-celiac wheat sensitivity
Part of Digestive system clinical trials.
This study looks at how different types (genotypes) of wheat affect gut symptoms in people who react to wheat but do not have celiac disease. It may help clarify which wheat triggers symptoms and how to confirm the trigger in a structured food challenge.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Blood tests show you are negative for celiac-related antibodies (tissue transglutaminase and endomysium)
- Your biopsy (if you had one) does not show damage to the small intestine lining (no villous atrophy)
- You test negative for an allergy type reaction to wheat (skin prick and/or wheat-specific IgE blood tests)
- Your symptoms have been present after diagnosis for more than 12 months, with at least two clinic visits
- Your symptoms improved on an elimination diet and came back during a controlled “double-blind” wheat challenge
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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