Clin2
NCT03417856Possibly a fitEnrolling by invitation

Study skin and blood signs in ichthyosis

IchthyosisNetherton Syndrome

Part of Genetic & congenital, Skin clinical trials.

This study looks at “skin and blood biomarkers,” meaning measurable signs in the body, in people with ichthyosis to better understand the condition. It may help researchers find ways to track disease activity and evaluate future treatments.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
1 year to 60 years
Study type
Observational

Who can take part

  • Be between 1 and 60 years old when you enroll
  • If you have ichthyosis, your diagnosis must be Netherton syndrome, lamellar ichthyosis, or another ichthyosis type
  • For ichthyosis: avoid anti-inflammatory pills by 1 month before blood/skin sampling
  • For ichthyosis: avoid anti-inflammatory creams by 1 week before sampling
  • For skin sampling: do not apply lotions (emollients) to the exact biopsy spots within 12 hours before the biopsy

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07783165Not yet recruiting
Studying the safety and moisturizing effect of Doublebase Once for ichthyosis

This trial tests a moisturizer called Doublebase Once in people with ichthyosis (a condition causing dry, scaly skin). For one month, you'd use this product once daily instead of your usual moisturizer to see if it works well and is safe.

NCT07280091Recruiting
Skin and gut bacteria in Netherton syndrome

This study looks at the bacteria on the skin and in the gut of people with Netherton syndrome, a condition that affects the skin barrier and often causes allergies. It also compares these findings to healthy volunteers to understand how the microbiome might be different.

Paris, Île-de-France Region
NCT06362447Not yet recruiting· Phase 2
Gentamicin injections for hereditary ichthyosis

This study tests whether an antibiotic called gentamicin, given as an injection, can improve symptoms of hereditary ichthyosis, a genetic skin condition that causes severe dryness and scaling. If you have moderate to severe ichthyosis due to certain gene changes, this treatment might help your skin produce the missing proteins.

Paris, France
NCT06545695Not yet recruiting· Phase 1/Phase 2
Testing a pill for skin conditions caused by keratin gene changes

This study tests an oral medication called erlotinib (an EGFR inhibitor) to see if it can reduce the skin symptoms of keratinopathies like epidermolytic ichthyosis, epidermolytic palmoplantar keratoderma, and pachyonychia congenita. The goal is to improve skin condition and quality of life.

Chicago, Illinois
NCT07477769Not yet recruiting
Blood cell study for inherited ichthyosis with NIPAL4 gene mutation

This study looks at blood cells in people with a rare form of ichthyosis caused by NIPAL4 gene mutations. It aims to understand how the immune system might be affected, which could help improve future care.

NCT06599411Recruiting
Skin biomarkers for inflammatory disease treatment

This study looks for clues in your skin and blood that could predict how well you'll respond to treatments for conditions like eczema, psoriasis, or lupus. It aims to help doctors choose the best therapy for you.

Paris

Hear when a new Ichthyosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.