Gentamicin injections for inherited ichthyosis
Treatments studied
Part of Genetic & congenital, Skin clinical trials.
This trial tests if gentamicin injections can improve symptoms of hereditary ichthyosis, a genetic skin condition. It is for adults with moderate to severe forms caused by specific gene mutations.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18–75 years old
- You must have a specific genetic mutation (non-sense mutation) in one of these genes: TGM1, PNPLA1, ALOX12B, NIPAL4, ALOXE3, SDR9C7, ABCA12, CERS3, SPINK5, or CDSN
- You must have moderate to severe ichthyosis, with at least two body areas affected (back, arms, legs, or feet)
- You must not have used gentamicin or similar antibiotics in the last 3 months
- You must not have kidney problems or hearing loss not caused by earwax
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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