Clin2
NCT03676049Worth exploringAvailable

Cannabidiol for severe childhood epilepsy

Drug Resistant Epilepsy

Treatments studied

Part of Brain & nervous system clinical trials.

This trial provides access to cannabidiol (CBD), a marijuana-derived compound, for children with severe epilepsy that hasn't improved with standard medications. The goal is to see if CBD can help reduce seizures in this difficult-to-treat group.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Ages
5 years to 19 years
Study type
Expanded Access

Who can take part

  • Age 5 to 19 years old
  • Seizures not controlled by at least three different anti-seizure medicines
  • On 1 to 3 anti-seizure medicines at the same dose for at least 4 weeks before starting
  • Significant developmental delays, such as not speaking and not walking without help
  • No use of CBD or other cannabis products for at least 1 month before starting
  • Must be able to attend all study visits and follow study rules

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07023744Not yet recruiting· Phase 2
Cannabis-based medicine for hard-to-treat seizures

This study tests whether a cannabis-based medicine can reduce seizures in people with epilepsy that hasn't improved with other treatments. It may offer a new option for those who continue to have seizures.

NCT06309251Recruiting
Ketogenic diet for children with epilepsy or other conditions

This trial studies how well a ketogenic diet works for children with hard-to-treat epilepsy or certain other diseases. It aims to see if the diet improves quality of life.

Milan, MI
NCT02397863AVAILABLE
Cannabidiol for children with hard-to-control seizures

This trial tests an oral cannabidiol medicine (Epidiolex) for children whose seizures are not controlled by other treatments. It aims to see if adding this drug can reduce seizure frequency.

Augusta, Georgia
NCT07668856Recruiting· Phase 3
CBD for children with hard-to-treat epilepsy

This trial tests if adding cannabidiol (CBD) to your child's current seizure medicines can reduce seizures. It uses a personalized approach to see if CBD works for each child.

Utrecht, Utrecht
NCT07564245Not yet recruiting· Phase 2
Cannabidiol for self-injury in children with severe developmental disorders

This trial tests whether a medication called cannabidiol (a cannabis-derived compound) can reduce severe self-injury behaviors in children and teens with severe neurodevelopmental disorders. It aims to see if it's safe and effective when other treatments haven't worked.

Paris, Île-de-France Region
NCT06924827Not yet recruiting· Phase 4
Switching from artisanal CBD to Epidiolex for children with Dravet or Lennox Gastaut syndrome

This study looks at what happens when children with Dravet or Lennox Gastaut syndrome switch from a homemade or artisanal CBD product to Epidiolex, a prescription CBD. The goal is to see if the switch is safe and helps control seizures.

Toronto, Ontario

Hear when a new Drug Resistant Epilepsy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.