Clin2
NCT03941080Possibly a fitRecruiting

Study gut bacteria changes in advanced colorectal cancer

Colorectal Cancer Metastatic

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study looks at how gut bacteria (the microbiome) change during treatment for colorectal cancer that has spread or cannot be removed. Researchers hope the findings may help improve understanding of how treatment works and how to tailor care.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
300 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You have confirmed colorectal cancer that is advanced and needs palliative (symptom-focused) cancer medicine.
  • Your cancer has measurable spots on scans (according to RECIST 1.1).
  • You have stored tissue samples available from previous testing or procedures.
  • You can live at least 12 more weeks and are able to follow the study plan; you sign consent to join.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07486492Not yet recruiting· Early Phase 1
Testing if healthy gut bacteria can boost immunotherapy for advanced bowel cancer

This trial tests whether transferring healthy gut bacteria can help make immunotherapy more effective for people with advanced bowel cancer that didn't respond to standard treatments.

NCT05501353Recruiting
Study tumor biomarkers in recurrent metastatic colon cancer

This study looks for blood/tumor signals (“biomarkers”) that may help predict outcomes in people whose colorectal cancer returns and spreads after surgery. It mainly helps researchers understand who may do better or worse, which can guide future care.

Hangzhou, Zhejiang
NCT07154173Recruiting
Gut bacteria study in metastatic colorectal cancer

This study looks at gut bacteria in people with colorectal cancer that has spread (metastatic). It aims to find patterns in the bacteria that may help doctors choose better treatments.

Guangzhou, Guangdong
NCT03841799Recruiting
Study of gut bacteria and immune changes in colon tissue

This study looks at how gut bacteria and immune activity differ in normal, pre-cancer, and cancer colon tissue. It may help researchers understand what changes in the body are linked to colon growth and how they could be targeted in the future.

Lyon, Lyon
NCT06734156Recruiting
Gut microbiome study in colorectal cancer patients

This study looks at how bacteria and other microbes in your gut are linked to colorectal cancer risk and outcomes. By collecting stool samples from people newly diagnosed with colorectal cancer, researchers hope to find patterns that could improve understanding and future treatments.

Lisbon, Lisbon District
NCT06331988Recruiting
Study of colon cancer, bacteria, and the immune system

This study looks at how bacteria in your gut, your immune system, and colon cancer interact. It aims to understand these connections to improve future treatments.

Milan

Hear when a new Colorectal Cancer Metastatic trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.