Study gut bacteria changes in advanced colorectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study looks at how gut bacteria (the microbiome) change during treatment for colorectal cancer that has spread or cannot be removed. Researchers hope the findings may help improve understanding of how treatment works and how to tailor care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have confirmed colorectal cancer that is advanced and needs palliative (symptom-focused) cancer medicine.
- Your cancer has measurable spots on scans (according to RECIST 1.1).
- You have stored tissue samples available from previous testing or procedures.
- You can live at least 12 more weeks and are able to follow the study plan; you sign consent to join.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving healthy gut bacteria can help standard immune treatment work better for advanced bowel cancer that has not responded to initial therapies.
This study looks for blood/tumor signals (“biomarkers”) that may help predict outcomes in people whose colorectal cancer returns and spreads after surgery. It mainly helps researchers understand who may do better or worse, which can guide future care.
This study looks at gut bacteria in people with colorectal cancer that has spread (metastatic). It aims to find patterns in the bacteria that may help doctors choose better treatments.
This study looks at how gut bacteria and immune activity differ in normal, pre-cancer, and cancer colon tissue. It may help researchers understand what changes in the body are linked to colon growth and how they could be targeted in the future.
This study tests whether adding a fecal microbiota transplant (a way of putting healthy gut bacteria into your colon) to the standard first-line chemotherapy and targeted therapy can help control advanced colorectal cancer that cannot be surgically removed. The goal is to see if this combination works better than standard treatment alone.
This study looks at how bacteria and other microbes in your gut are linked to colorectal cancer risk and outcomes. By collecting stool samples from people newly diagnosed with colorectal cancer, researchers hope to find patterns that could improve understanding and future treatments.
Hear when a new Colorectal Cancer Metastatic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.