Adding healthy gut bacteria to standard first-line therapy for advanced colorectal cancer
Part of Cancer, Digestive system clinical trials.
This study tests whether adding a fecal microbiota transplant (a way of putting healthy gut bacteria into your colon) to the standard first-line chemotherapy and targeted therapy can help control advanced colorectal cancer that cannot be surgically removed. The goal is to see if this combination works better than standard treatment alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with advanced colorectal cancer that cannot be removed with surgery at this point.
- You have not yet received standard first-line treatment (like chemotherapy or targeted therapy) for this cancer.
- You are generally able to care for yourself and are up and about more than half of the day (ECOG 0-1).
- Your major organs (bone marrow, liver, kidneys, heart) are working well enough, based on standard blood tests and heart check.
- You are willing to use effective birth control during the study and for 6 months after the last dose (if you could become pregnant or father a child).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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