Clin2
NCT03945448Possibly a fitRecruiting

Single-dose antifungal for people with HIV and positive cryptococcal blood test

Cryptococcal Meningitis

Treatments studied

Part of Brain & nervous system, Infections clinical trials.

This study tests whether a one-time antifungal treatment can help people with HIV who have a positive cryptococcal antigen blood test but no symptoms. It may lower the chance that this infection becomes a serious illness affecting the brain.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
356 people
Ages
15 years and older
Study type
Interventional

Who can take part

  • You have HIV infection (HIV-1).
  • You are 15 years old or older.
  • You can and are willing to sign informed consent (agree to take part).
  • Your blood test for cryptococcal antigen (CRAG) is positive at a level of at least 1:160.
  • You can attend regular clinic visits as the study requires.
  • You have no known allergy to amphotericin.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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