Chemo before surgery for middle-lower esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a chemotherapy combination (nab-paclitaxel plus cisplatin) given before surgery for locally advanced, operable esophageal squamous cell cancer. It aims to shrink the tumor and improve outcomes by treating cancer earlier while it’s still in one region.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- You have esophageal squamous cell cancer (not adenocarcinoma) that is resectable (can be removed) and has no distant spread
- You have not had any prior cancer treatment that works throughout the body for this cancer (including chemo, immunotherapy, targeted therapy, or systemic therapy)
- Your general health and strength are good (ECOG performance status 0–1)
- Your organs (bone marrow, liver, and kidneys) and blood clotting must meet lab thresholds before surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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