Clin2
NCT06446726Possibly a fitRecruiting

Low-dose radiation, chemo, and immunotherapy before esophageal cancer surgery

Esophageal Squamous Cell Carcinoma

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of low-dose radiation, chemotherapy, and immunotherapy before surgery for esophageal cancer. The goal is to see if this approach helps shrink the tumor and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have a specific type of esophageal cancer called squamous cell carcinoma, and it hasn't spread to distant organs.
  • You are well enough to have surgery to remove the tumor, and your doctor believes it can be completely removed.
  • You are between 18 and 75 years old and able to perform daily activities with little to no help (ECOG score 0-1).
  • Your blood counts, liver, kidney, and lung function are within healthy ranges.
  • You have not had prior treatment for this cancer, including chemotherapy, radiation, or immunotherapy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07312578Enrolling by invitation· Phase 2
Targeted drugs plus chemo before surgery for esophageal cancer

This trial tests a combination of two targeted drugs (nimotuzumab and camrelizumab) plus standard chemotherapy before surgery for people with esophageal squamous cell carcinoma. The goal is to see if this approach helps shrink the tumor and improve outcomes.

Beijing, Beijing Municipality
NCT07699185Recruiting· Phase 2
Immunotherapy plus chemoradiation before surgery for esophageal cancer

This study tests whether giving a combination of chemotherapy, radiation, and an immunotherapy drug (cadonilumab) before surgery can help shrink esophageal cancer and improve outcomes. It is for people with a specific type of esophageal cancer that has not spread to other parts of the body.

Wuhan, Hubei
NCT03964753Recruiting· Phase 2
Chemo before surgery for middle-lower esophageal cancer

This trial tests a chemotherapy combination (nab-paclitaxel plus cisplatin) given before surgery for locally advanced, operable esophageal squamous cell cancer. It aims to shrink the tumor and improve outcomes by treating cancer earlier while it’s still in one region.

Shijiazhuang, Hebei
NCT06509568Recruiting· Phase 2
Chemoradiation plus immunotherapy before surgery for esophageal cancer

This trial tests giving a combination of chemotherapy, radiation therapy, and an immunotherapy drug before surgery for a type of esophageal cancer (squamous cell). The goal is to see if this approach helps shrink the tumor and improve outcomes for patients whose cancer can be surgically removed.

Hangzhou, Zhejiang
NCT06178211Not yet recruiting· Phase 2
Drug plus chemo before surgery for esophageal cancer

This trial tests a drug called Adebrelimab combined with chemotherapy before surgery for esophageal cancer. It aims to shrink the tumor and make it easier to remove completely.

Shanghai
NCT06303583Enrolling by invitation· Phase 1/Phase 2
Chemo-radiation followed by immunotherapy for esophageal cancer

This trial tests if giving chemotherapy and radiation before surgery, followed by immunotherapy, can improve outcomes for people with a specific type of esophageal cancer that can be surgically removed.

Hangzhou, Zhejiang

Hear when a new Esophageal Squamous Cell Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.