Uterus transplant study for people with uterine infertility
Part of Women’s health & pregnancy clinical trials.
This trial looks at whether transplanting a deceased donor uterus can allow pregnancy for people who cannot conceive because their uterus does not work or is absent. You would also need to take anti-rejection medicines and come to frequent follow-up visits after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your doctor at Brigham and Women’s Hospital has confirmed you have uterine infertility (AUIF).
- You can make at least 6 healthy (euploid) embryos for freezing before transplant.
- Your BMI is 30 or less, and your kidney function test (GFR) is at least 60.
- Your immune test (PRA) is 20% or less.
- You must be able to follow a strict medicine schedule and attend required follow-up visits, with support at home for a child.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies uterus transplant surgery to help people with “absolute uterine factor infertility” (no working uterus) become pregnant using embryos made by IVF. It checks whether the donated uterus can support pregnancy and safe delivery for participants who meet strict medical and health requirements.
This trial tests whether receiving a donated uterus can allow pregnancy in women who cannot become pregnant because of an absent or non-working uterus. It also looks at safety and how well the pregnancy and follow-up medicines work after transplant.
This trial studies transplanting a uterus to allow people with uterine infertility to try pregnancy. It may help some patients who cannot carry a baby because their uterus is missing or nonfunctional, but it requires careful matching and strict health screening for both recipients and donors.
This study tests whether transplanting a uterus can help people who cannot carry a pregnancy become pregnant and give birth. It involves surgery plus medicines to help the body accept the new organ, and then embryo transfer to try to achieve pregnancy.
This trial looks at people’s acceptance and experience of receiving a uterus transplant. It may help researchers understand how to support patients considering this option, especially who are younger and have specific health requirements.
This trial tests whether receiving a uterus transplant can allow someone with uterine absence to carry a pregnancy. It also looks at whether the procedure is safe for the patient and supports a future baby using frozen embryos.
Hear when a new Infertility of Uterine Origin trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.