Clin2
NCT04135807Possibly a fitRecruiting

Implantable device test for operable brain tumor patients

Grade II GliomaGrade III GliomaGrade IV GliomaAstrocytomaOligodendroglioma of BrainAnaplastic Astrocytoma of BrainAnaplastic OligodendrogliomaGlioblastoma

Part of Cancer clinical trials.

This early-phase trial tests a tiny implanted device placed during brain tumor surgery. It delivers very small doses of medicine directly to the tumor area for a short time, aiming to see if this approach is safe and workable in patients with certain gliomas.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
12 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have an operable brain tumor in the upper (outer) part of the brain that the surgery team plans to remove partly or completely.
  • Your tumor is expected to be a type of brain cancer called grade 2–4 glioma (often confirmed during surgery).
  • You are age 18 or older, and your overall strength/ability to function is good enough for surgery (Karnofsky score 60 or higher).
  • Your blood tests and organ function (kidneys, liver, blood counts) are within required limits.
  • Your neurosurgeon reviews your tumor location and decides the device can be placed safely.
  • If you could become pregnant: you must have a negative pregnancy test and use reliable birth control; breastfeeding must be stopped if you take part.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06804655Not yet recruiting· Phase 2
Personalized drug testing for stubborn brain tumors

This study tests a new way to choose treatment for people with brain tumors that have not responded to standard therapies. Your tumor sample is analyzed in the lab to find which drugs might work best for you, and then you receive a personalized treatment plan.

Basel, Basel-Landschaft
NCT06512311Recruiting
Personalized drug testing for newly diagnosed glioblastoma

This trial tests whether testing drugs on your tumor cells in a lab can help find the best treatment for you. It is for people with a specific type of glioblastoma that has not been treated yet.

Vienna, State of Vienna
NCT05565118Recruiting· Phase 1
Brain activity study during surgery for high-grade glioma

This early-stage study measures electrical brain activity during brain tumor surgery to see if it can predict tumor return or progression. You may be offered the additional measurements while your surgeon removes a suspected or known high-grade glioma.

Cleveland, Ohio
NCT06623565Recruiting
Advanced imaging for extensive brain tumor removal

This trial uses advanced imaging to help surgeons remove as much of a malignant brain tumor as safely possible. It may be a good fit if you have a new diagnosis of glioblastoma or a certain astrocytoma and are healthy enough for surgery.

Amsterdam, North Holland
NCT05839379Recruiting
Targeted therapy study for children and young adults with brain tumors

This trial studies a targeted medicine approach for high-grade glioma (a fast-growing brain tumor) and some diffuse midline tumors, including DIPG. It may help by matching treatment to tumor biology using tumor testing done before or around starting standard therapy.

Aurora, Colorado
NCT06136611Recruiting
Pre-surgery Optune for glioblastoma

This trial tests whether wearing a device called Optune (which uses electric fields to slow cancer growth) before surgery helps people with glioblastoma. It is for patients who are fairly active and plan to have standard tumor removal and radiation therapy afterward.

Manchester

Hear when a new Grade III Glioma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.