Liver transplant for stable advanced bile duct cancer
Part of Cancer clinical trials.
This trial looks at liver transplant for people with advanced intrahepatic cholangiocarcinoma (a bile duct cancer inside the liver) when the cancer is not safely removable and stays controlled. It may help some patients live longer and with better quality of life by replacing the diseased liver—if strict safety and disease-stability requirements are met.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 or older and able to sign consent paperwork.
- Your general health/energy is good (doctor rates you as 0 or 1 on the ECOG scale).
- Your cancer diagnosis is confirmed as intrahepatic cholangiocarcinoma from a biopsy.
- Scans show the cancer is only in the liver (no lymph node involvement, no blood-vessel invasion, and no spread outside the liver).
- Your cancer has been stable or shrinking for at least 6 months on gemcitabine-based treatment (or, if you needed a second treatment line, controlled for at least 6 months on that line too).
- You have at least one living donor who is compatible by blood type and passes the donor health screening.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests if a liver transplant can help people with a type of bile duct cancer that can't be removed with surgery. You may join if the cancer has stayed stable or shrunk for at least 6 months with treatment.
This trial tests if a liver transplant can help people with a certain type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. Before the transplant, you would receive radiation therapy (SIRT) and chemotherapy to shrink the tumor.
This trial studies whether a liver transplant can help people with a non-removable type of bile duct cancer in the liver. To be eligible, the cancer must be in the liver only (no spread), and you typically must already have had at least 6 months of treatment before being listed for transplant.
This trial tests if a liver transplant can help people with a certain type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be surgically removed. You must have had at least six months of chemotherapy and your cancer must be stable or smaller before you can be listed for a transplant.
This trial tests whether a liver transplant from a living donor can help people with a certain bile duct cancer that hasn't spread. It is for patients whose cancer is stable or smaller after chemotherapy.
This study tests if a liver transplant can help people with a type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be surgically removed. It is for patients whose cancer has been stable for at least 6 months after initial treatments.
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