Living donor liver transplant for bile duct cancer
Part of Cancer clinical trials.
This trial tests whether a living donor liver transplant can help people with a certain type of liver cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. It is for patients whose cancer has not spread and who have responded well to chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of liver cancer called intrahepatic cholangiocarcinoma that cannot be surgically removed.
- Your cancer is low or medium grade (G1 or G2), not high grade (G3).
- Your cancer has not spread outside the liver, confirmed by imaging tests.
- Your cancer has stayed stable or shrunk after chemotherapy, and you have had a special radiation treatment (SIRT) to the liver.
- You have a living donor who is blood-type compatible and willing to donate part of their liver.
- You are 18 years or older and able to give informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new surgical approach that removes the liver, pancreas, and bile duct all at once (and then gives a liver transplant) for people with a type of bile duct cancer that cannot be removed with standard surgery. It may help people whose cancer is limited to the liver area and who have not responded to other treatments.
This trial looks at liver transplant for people with advanced intrahepatic cholangiocarcinoma (a bile duct cancer inside the liver) when the cancer is not safely removable and stays controlled. It may help some patients live longer and with better quality of life by replacing the diseased liver—if strict safety and disease-stability requirements are met.
This trial tests if a liver transplant can help people with a certain type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. Before the transplant, you would receive radiation therapy (SIRT) and chemotherapy to shrink the tumor.
This trial studies whether a liver transplant can help people with a non-removable type of bile duct cancer in the liver. To be eligible, the cancer must be in the liver only (no spread), and you typically must already have had at least 6 months of treatment before being listed for transplant.
This trial tests if a liver transplant can help people with a certain type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be surgically removed. You must have had at least six months of chemotherapy and your cancer must be stable or smaller before you can be listed for a transplant.
This trial studies liver transplantation for people with a specific type of bile duct cancer near the liver that cannot be safely removed by surgery. It aims to improve outcomes by offering a transplant after the cancer responds to chemotherapy and spread has been ruled out on scans.
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