HIPEC plus FLOT versus FLOT alone for gastric or GE junction cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial compares two treatment approaches after your stomach/GE junction cancer has been treated with chemotherapy before surgery: adding a special heated bath into the abdomen (HIPEC) plus continuing the usual surgery plan. It aims to see if adding HIPEC lowers cancer coming back and improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed stomach or gastroesophageal junction adenocarcinoma that can be removed with surgery
- Your cancer treatment before study must be 3 to 6 cycles of FLOT chemotherapy
- You must not have had other chemo or targeted drugs before—only FLOT
- Your scans must show no distant spread (no metastases), and nearby organs must not be invaded
- A laparoscopy (small camera surgery) must not show cancer spread on the lining of the belly (peritoneal disease)
- Your heart, liver, kidneys, and blood tests must be good enough for major surgery and HIPEC
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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