Immunotherapy plus surgery versus immunotherapy alone for kidney cancer
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether adding surgery to remove the kidney improves outcomes compared with continuing immunotherapy without surgery. It is for people with metastatic kidney cancer whose disease has not worsened after initial immunotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have kidney cancer of a specific type: clear cell or non-clear cell (not collecting duct type).
- Your primary kidney tumor is still present (no kidney removal yet).
- You have metastatic disease on recent imaging: CT of chest and CT/MRI of abdomen-pelvis done within the last 90 days (or per study timing).
- You must be able to safely undergo nephrectomy (kidney removal) with no clear reasons surgery is unsafe.
- You cannot have active brain metastases (past treated brain spots are allowed if you have no brain symptoms).
- After starting immunotherapy, scans about 12 weeks later must show stable disease/partial response or doctor-confirmed benefit (and you plan to keep the immunotherapy).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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