Drug-coated balloon for artery disease below the knee
Part of Heart & circulation clinical trials.
This trial tests a drug-coated balloon to open narrowed or blocked arteries in the lower leg (below the knee) and help them stay open. It’s meant for people with significant symptoms, to reduce re-narrowing after treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 21 years old or older
- Have severe below-the-knee circulation problems (Rutherford class 4 to 6) in the leg being treated
- The blocked/narrowed spot is in the below-the-knee arteries and is 2 to 20 cm long
- Blood must reach the foot after treatment (no major blockage at the end of the artery path)
- You should not be pregnant, trying to become pregnant, or have heel gangrene
- No serious medical conditions likely to shorten life expectancy to 1 year or less
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two balloon treatments used during a procedure to open blocked or narrowed arteries in the thigh and behind the knee. It tests whether the sirolimus-coated balloon works better at keeping the artery open than a standard balloon.
This trial tests a special balloon coated with sirolimus (a drug that helps prevent arteries from re-closing) versus a standard balloon for opening blocked arteries below the knee in people with severe leg pain or foot wounds. The goal is to see if the drug-coated balloon works better to keep the artery open longer.
This trial tests whether a drug-coated balloon can better reopen blocked arteries in the lower leg (below the knee). It may help keep blood flow open and reduce the chance the blockage comes back, after a procedure to cross and open the narrowed area.
This trial tests a special balloon coated with a drug (paclitaxel) to open blocked leg arteries, aiming to improve blood flow and reduce symptoms like leg pain when walking. It is for people with moderate to severe leg artery disease who have not had prior stents or bypass in the treated area.
This study tests whether a special “drug-eluting” stent placed in a leg artery works safely and improves blood flow for people with peripheral artery disease. It may help reduce re-narrowing and improve walking, depending on your blockage details and overall health.
This trial tests a drug-coated balloon to open blocked or narrowed arteries in the leg (above the knee). It may help improve blood flow and reduce symptoms like pain or sores.
Hear when a new Peripheral Artery Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.