Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,968 recruiting studies in this area right now.
By phase
- Not applicable7,950
- Phase 2484
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke839
- Heart Failure566
- Hypertension399
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma334
- Atrial Fibrillation269
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Acute Coronary Syndrome82
- Peripheral Arterial Disease82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama196
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,965 total
- NCT02504853Recruiting
Study food allergy patterns and genetics over time
This study follows people with food allergy and some closely related or healthy people to learn how food allergy (and related conditions) develops over time. It may help researchers find causes and better ways to predict and treat food allergy.
Bethesda, MarylandAges 1 day–99 years - NCT07613918Recruiting
Brain Blood Flow Monitoring in Critically Ill Children
This study measures how well blood flows to your child's brain while they're in the intensive care unit on a breathing machine. Understanding this flow may help doctors better care for critically ill children.
Madison, WisconsinAges 1 day–17 years - NCT07009639Recruiting
AI-powered heart ultrasound study
This study uses artificial intelligence to analyze heart ultrasound images from patients hospitalized with serious heart conditions. It aims to improve how doctors predict patient outcomes.
CosenzaAges 18–85 - NCT07009067Recruiting
Exercise after surgery for aortic dissection: a safety study
This study tests whether a supervised exercise program is safe and helpful for people who have had surgery for a type of aortic tear (type B aortic dissection). It aims to see if exercise can improve recovery without causing complications.
Guangzhou, GuangdongAges 18–75 - NCT07004452Recruiting
Predicting heart risks in younger adults with early heart disease
This study uses a multi-modal approach to predict adverse events in adults aged 18-45 with premature coronary heart disease. It aims to improve risk prediction and management for younger patients.
BeijingAges 18–45 - NCT06932484Recruiting
Delta variation to guide hemodynamic optimization
This trial studies whether using a measure called delta variation can help guide fluid and medication management during major abdominal surgery. It aims to improve blood flow and overall outcomes for patients.
Rome, RMAges 18 years+ - NCT06480305Recruiting
Evening snacks and pre-breakfast intake in healthy men
This study looks at how eating an evening snack before bed and having a small pre-breakfast meal affects sleep quality, heart rate, and stress levels in healthy men. It may help you understand how meal timing affects your body.
Islamabad, Punjab ProvinceAges 30–50 - NCT05793502Recruiting
Testing a heart pacing method with specific new devices
This trial studies how safe and effective a newer type of heart pacing (LBBaP) is when using two specific commercial devices. It may help people who are getting their first permanent pacemaker or heart-resynchronization treatment (CRT) by comparing outcomes after the procedure.
Taiyuan, ShanxiAges 18 years+ - NCT05328856Recruiting
Vital shower study to improve well-being and body regulation
This trial studies whether a special “vital shower” can improve quality of life, immune-related measures, heart/blood-pressure regulation, and overall well-being. You may be a fit if you’re generally healthy enough and can safely use the shower setup during the study.
Berlin, State of BerlinAges 18–70 - NCT05209841Recruiting
Heparin versus saline to keep IV line working
This trial compares using heparin (a blood-thinning medicine) versus saline (salt water) to keep a peripheral IV line open and working. It may help reduce line blockage and improve how well IV treatments can be given.
Sant Pere de Ribes, BarcelonaAges 18–100 - NCT05163925Recruiting
Study of a heart-lung device for emergency life support
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
ViennaAges 18 years+ - NCT03111173Recruiting
Check if a standard ECG can record your baby’s heart activity
This study tests whether a routine heart recording test (ECG) can capture fetal (baby) heart activity during late pregnancy. It may help researchers find simpler ways to monitor baby heart rhythm without special equipment.
Seattle, WashingtonAges 18–55 - NCT07777341Recruiting
Red grape juice and heart health in men
This study tests whether drinking red grape juice every day for a period can improve metabolism in men with coronary artery disease (blocked or narrowed heart arteries). If you have heart disease and are not diabetic, this could be a simple dietary addition to support your heart health.
São Paulo, São PauloAges 46–69 - NCT07594041Recruiting
Videos for heart care education in children
This study tests whether short educational videos help caregivers of children with heart conditions understand their child's diagnosis and care plan better than standard spoken information alone.
San Antonio, TexasAges Up to 18 years - NCT07792655Recruiting
Hand therapy at home after stroke
This study tests a therapy program done at home using video calls to help improve hand function after a stroke. It may help you regain better use of your hand if you had a stroke at least 6 months ago.
Ann Arbor, MichiganAges 40–75 - NCT07792694Recruiting
Predicting dangerous heart rhythms with smart software
This study uses computer software to analyze heart rhythm recordings from patients in the hospital to predict dangerous irregular heartbeats (arrhythmias). It aims to improve early detection and care for patients with heart conditions.
Eindhoven, North BrabantAges 18 years+ - NCT07454980Recruiting
Tricuspid valve replacement for severe leakage (TRINITY trial).
This trial tests a new catheter-based replacement for the tricuspid valve, which controls blood flow from the body into the heart. It aims to help people with severe tricuspid regurgitation (a leaky valve) who still have symptoms despite medication.
Naples, FloridaAges 21 years+ - NCT07792239RecruitingPhase 2
Study of budiodarone for atrial fibrillation
This study tests a new medicine, budiodarone, to help control atrial fibrillation (an irregular heartbeat) in people who haven't been helped by other treatments. It may reduce the time spent in AF and improve symptoms.
GdyniaAges 18–80 - NCT07764094Recruiting
Balloon treatment for blocked heart arteries
This trial tests how the way a drug-coated balloon is used during a heart procedure affects outcomes for people with stable heart disease or unstable angina. It may help doctors find the best technique to keep arteries open.
Chuzhou, AnhuiAges 18–80 - NCT07137455Enrolling by invitation
New system to record and classify heart electrical signals
This trial is testing a new recording system that helps doctors see and classify the heart's electrical signals during a routine heart procedure. It may improve how doctors treat abnormal heart rhythms or place pacemakers.
Atlanta, GeorgiaAges 21–100 - NCT06736574RecruitingPhase 3
Study of omecamtiv mecarbil for chronic heart failure with very weak heart pump
This study tests an investigational medicine (omecamtiv mecarbil) for people with chronic heart failure and very low pumping strength. It looks at whether the drug can help prevent heart failure events or the need for stronger treatments.
Alexander City, AlabamaAges 18–85 - NCT07075185RecruitingPhase 1
Gene therapy study for hard-to-treat multiple myeloma
This study tests a new gene therapy for people with multiple myeloma that has come back or stopped responding to at least 3 prior treatments. The therapy is designed to help your immune system fight the cancer cells more effectively.
Duarte, CaliforniaAges 18 years+ - NCT05714085RecruitingPhase 2/Phase 3
Vericiguat study for children with heart failure
This trial tests whether vericiguat helps children with chronic heart failure caused by weaker left heart pumping. It also checks safety and how the medicine behaves in the body (dose and processing).
Los Angeles, CaliforniaAges 4 weeks–17 years - NCT06642246Recruiting
Sleep Help for Kids with High Blood Pressure
This study tests whether helping teens with high blood pressure get more sleep can lower their blood pressure. It offers a sleep-focused program and checks if it helps within a few months.
Philadelphia, PennsylvaniaAges 13–18
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,968 recruiting cardiology studies from the U.S. registry right now, out of 15,149 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.