Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,602 recruiting studies in this area right now.
By phase
- Not applicable7,631
- Phase 4471
- Phase 2468
- Phase 3436
- Phase 1349
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure535
- Hypertension388
- Cardiovascular Diseases374
- Coronary Artery Disease364
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)153
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases59
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital51
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University47
- Johns Hopkins University45
Where studies are running
- California454
- Alabama196
- Arizona180
- Massachusetts172
- New York168
- Florida139
- Texas122
- Maryland118
- Minnesota117
- Illinois113
Recruiting studies9,602 total
- NCT07462741Recruiting
Education program for diabetic hemodialysis patients
This study tests if a special education program helps people with diabetes who are on hemodialysis (a type of kidney treatment). The goal is to see if learning more about managing their health can improve their overall well-being.
Elâzığ, MerkezAges 18 years+ - NCT06307262Recruiting
European registry for tricuspid valve repair
This trial is a registry that collects information on patients who have had a minimally invasive procedure to fix a leaky tricuspid valve. By joining, you help doctors learn more about how well these devices work over time.
Munich, BavariaAges 18 years+ - NCT07192952RecruitingPhase 3
Long-term safety of finerenone for children with heart failure
This trial tests a medicine called finerenone to see if it is safe for children and young adults with heart failure when taken for a long time. It may help improve heart function and manage symptoms.
Aurora, ColoradoAges Up to 18 years - NCT06321302RecruitingPhase 2
Study of BI 764524 for diabetic retinopathy
This study tests an investigational drug called BI 764524 for people with moderate to severe diabetic retinopathy, a complication of diabetes that can damage the retina. The goal is to see if the treatment can help prevent vision loss.
Phoenix, ArizonaAges 18 years+ - NCT07200102RecruitingPhase 1
Selinexor after CAR-T for high-risk multiple myeloma
This study tests whether taking selinexor after CAR-T cell therapy can help keep multiple myeloma from coming back. It is for people whose myeloma is high-risk or still has signs of disease after CAR-T.
St Louis, MissouriAges 18 years+ - NCT07141251Recruiting
Custom stent-graft procedure for complex aortic aneurysm repair
This study tests a new way to repair a complex aortic aneurysm (a bulge in the main artery) using a special procedure that helps keep blood flowing to your vital organs. It may help people who are not candidates for standard surgery. The goal is to see if this approach is safe and works well.
Beijing, Beijing MunicipalityAges 18–80 - NCT07188805RecruitingPhase 3
Finerenone for children with heart failure
This study tests a medicine called finerenone in children with heart failure. It looks at whether finerenone helps the heart work better and is safe compared to a placebo (a dummy pill), when taken with the usual heart-failure medicines.
Aurora, ColoradoAges 6 months–17 years - NCT05735704Recruiting
Blood cancer early detection study
This study looks for early signs of blood cancers in people who have them or are at higher risk, like family members or older adults. It aims to find cancer sooner, which may lead to better outcomes.
OlomoucAges 18 years+ - NCT07874594Recruiting
Brain training to improve sleep after a first stroke
This study tests a treatment that may help reduce brain inflammation and improve sleep in people who have had a first stroke and now have trouble sleeping. It uses a non-invasive technique called remote ischemic conditioning, which involves brief, repeated cycles of a blood pressure cuff on the arm.
Chengdu, SichuanAges 18–80 - NCT07562932Recruiting
Norepinephrine vs dopamine for cardiogenic shock
This study compares two blood pressure support medicines (norepinephrine and dopamine) in adults with cardiogenic shock, a condition where the heart cannot pump enough blood. It aims to find which medicine works better for patients with this severe heart condition.
Gwangju, Jeollanam-doAges 19 years+ - NCT07713615Recruiting
Blood clotting markers and heart ultrasound in people with device-detected atrial fibrillation
This study looks at blood clotting markers and heart ultrasound in people who have a heart device that detected brief episodes of irregular heartbeat (atrial fibrillation). It aims to understand how these markers relate to stroke risk.
EsbjergAges 50 years+ - NCT07876544RecruitingPhase 4
New drug plus amlodipine for high blood pressure and early kidney damage
This trial tests a new medicine (sitogilun malate) combined with a standard blood pressure drug (amlodipine) to see if it protects the kidneys in people with early kidney damage caused by high blood pressure. Participation could help prevent further kidney damage while controlling your blood pressure.
Shanghai, ChinaAges 18 years+ - NCT03545477Recruiting
Curved walking training for stroke, Parkinson's and hip fracture recovery
This study tests whether practicing walking in curved paths can help people recovering from a stroke, Parkinson's disease, or a recent hip fracture improve their balance and mobility. If you have one of these conditions and are in a rehabilitation program, this training might make everyday walking easier.
Lissone, Monza E BrianzaAges 18–90 - NCT07876479Recruiting
Comparing kidney nerve treatment times for high blood pressure
This study tests whether the length of time used for a kidney nerve treatment (renal denervation) affects how well it lowers blood pressure. It may help people whose blood pressure is still high despite taking medications.
ShanghaiAges 20–80 - NCT03631628Recruiting
Mirror therapy with gentle nerve stimulation for stroke arm recovery
This study tests whether combining mirror therapy with mild electrical nerve stimulation can help improve arm and hand movement after a stroke. It may be an option if you can move your unaffected arm and have some shoulder and wrist movement on your affected side.
Hong Kong, Hong KongAges 50–85 - NCT07874763Recruiting
Comparing two pacing sites for heart devices
This study compares two different places in the heart where a pacemaker or similar device's wire can be attached. The goal is to see if one spot works better than the other for patients getting their first heart device.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07875257Enrolling by invitation
Brain-based therapy for recovery after a left-side stroke
This study tests a new brain-computer system that helps people recovering from a stroke in the left side of the brain. It uses your thoughts to move a device, which may help improve arm and hand movement.
Buenos Aires, EscobarAges 18–65 - NCT06570473RecruitingPhase 2
RV failure treatment trial for pulmonary hypertension patients
This trial is testing two heart medications, empagliflozin and ranolazine, to see if they can improve right heart function in people with pulmonary hypertension and right ventricular failure. Participants will monitor their symptoms using a smartphone or tablet.
Calgary, AlbertaAges 18 years+ - NCT07875335Enrolling by invitation
Traditional Chinese medicine added to standard care for moyamoya disease
This trial tests whether a traditional Chinese herbal formula (Fufang Tongluo Decoction) can improve outcomes when added to aspirin and atorvastatin for people with moyamoya disease, a condition that narrows brain arteries and increases stroke risk. The study aims to see if this combination reduces stroke risk and improves overall well-being.
Nanjing, JaingsuAges 18–60 - NCT07686120RecruitingPhase 3
Baxdrostat for uncontrolled high blood pressure
This trial tests a new medicine called baxdrostat for people whose blood pressure stays high even when they take two or more medicines. It will be added to your current blood pressure pills to see if it helps lower your blood pressure more.
BeijingAges 18 years+ - NCT07830719RecruitingPhase 2
Study of a new drug for heart disease and inflammation
This study tests a new medicine called YMI024 for people with stable coronary artery disease (blockages in heart arteries) and higher than normal levels of inflammation. The drug aims to reduce inflammation and may lower the risk of future heart problems.
Fairhope, AlabamaAges 18–80 - NCT05610085RecruitingPhase 2
Levetiracetam for newborn seizures: dose-finding study
This trial studies how to give levetiracetam to newborn babies with seizures. It’s trying to find a safe dose and see if it can help control seizures in early life.
San Diego, CaliforniaAges Up to 1 month - NCT06904066RecruitingPhase 1
Personalized T cell therapy for blood cancers
This trial tests a treatment that takes your own immune cells, modifies them to attack cancer cells, and gives them back to you. It is for people with certain blood cancers who have specific gene changes.
Bethesda, MarylandAges 18–120 - NCT07490067RecruitingPhase 4
Metoprolol for heart failure: genes and drug response
This trial tests how the drug metoprolol works in people with heart failure and reduced pumping function. It looks at whether your genetic makeup affects how the drug is processed and how well it helps your heart.
Ann Arbor, MichiganAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,602 recruiting cardiology studies from the U.S. registry right now, out of 14,560 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.