Surgery and tumor testing in gastrointestinal stromal tumors (GIST)
Part of Cancer, Digestive system clinical trials.
This study looks at how surgery for gastrointestinal stromal tumors (GIST) works, and collects tumor samples to study them under the microscope and by DNA testing. Your results may help researchers better predict tumor behavior and guide future treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a suspected or confirmed GIST (tumor type), confirmed by pathology if possible using stored past tissue; a new biopsy may not be required if there isn’t enough tissue
- You are at least 6 years old
- You can do daily activities at an acceptable level (ECOG 0–2; or a similar score showing you can care for yourself)
- You or your parent/guardian can understand the study and agree by signing a consent form
- Your other health problems (that cannot be changed) must not be so severe that surgery would be unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether doing laparoscopic surgery for stomach GISTs (gastrointestinal stromal tumors) works and is safe when the tumor is in a “favorable” versus “unfavorable” location. You might be eligible if your tumor is confirmed as GIST and doctors expect to remove it completely using keyhole surgery.
This trial studies advanced GIST cancers that have stopped responding to all four standard treatments. It uses PET-CT scans and genetic testing of tumor tissue to understand resistance, helping to find the best next treatment.
This trial tests a new surgical approach combining laparoscopic (minimally invasive) surgery with endoscopy (a camera procedure) to remove small tumors located where the esophagus meets the stomach. The goal is to safely remove these tumors while preserving normal function.
This study is creating a registry to track people with GIST over time. Participating helps researchers learn more about the disease and improve future care.
This study looks at stomach (gastric) and esophagus cancer, using clinical information and tissue samples. It may help researchers better understand these cancers and improve future care.
This trial tests a new targeted therapy drug, DCC-3009, for people with advanced GIST that has a specific gene mutation (KIT or PDGFRA). It's for those who have already tried other targeted treatments and need a new option.
Hear when a new Gastric Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.